1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. mGluR
  4. mGluR7 Inhibitors

mGluR7 Inhibitors

mGluR1

mGluR2

mGluR3

mGluR4

mGluR5

mGluR6

mGluR7

mGluR8

mGluR

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform mGluR7 together.

Please try each isoform separately.

mGluR7 Specific Agonists, Antagonists & Modulators
Product Name mGluR7 mGluR1 mGluR2 mGluR3 mGluR4 mGluR5 mGluR6 mGluR8 mGluR7 Selectivity Purity
VU6012962
mGlu7, IC50: 347 nM
              Selective Modulator 99.92%
MMPIP hydrochloride
mGlu7
              Selective Antagonist
MMPIP
mGlu7
              Selective Antagonist
ADX71743
mGlu7
              Selective Antagonist
LY341495
mGluR7, IC50: 990 nM
mGluR1a, IC50: 7.8 μM
mGluR2, IC50: 21 nM
mGluR3, IC50: 14 nM
mGluR4, IC50: 22 μM
mGluR5a, IC50: 8.2 μM
 
mGluR8, IC50: 170 nM
Pan Antagonist 99.11%
L-APB
mGlu7, EC50: 249 μM
     
mGlu4, EC50: 0.13 μM
 
mGlu6, EC50: 1.0 μM
mGlu8, EC50: 0.29 μM
Pan Agonist ≥99.0%
VU6005649
mGlu7 Receptor, EC50: 0.65 μM
           
mGlu8 Receptor, EC50: 2.6 μM
Pan Agonist 98.67%
O-Phospho-L-serine
mGluR7
mGluR1
mGluR2
 
mGluR4
 
mGluR6
mGluR8
Pan Modulator ≥98.0%
DCG-IV
mGluR7, IC50: 40.1 μM
mGluR1R, IC50: 389 μM
mGluR2R, EC50: 0.35 μM
mGluR3R, EC50: 0.09 μM
mGluR4R, IC50: 22.5 μM
mGluR5, IC50: 630 μM
mGluR6, IC50: 39.6 μM
mGluR8, IC50: 32 μM
Pan Agonist
(RS)-PPG
hmGluR7b, EC50: 185 μM
     
hmGluR4a, EC50: 5.2 μM
 
hmGluR6, EC50: 4.7 μM
hmGluR8a, EC50: 0.2 μM
Pan Agonist