1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. mGluR
  4. mGluR7 Inhibitors

mGluR7 Inhibitors

mGluR8

mGluR6

mGluR7

mGluR5

mGluR4

mGluR3

mGluR2

mGluR1

mGluR

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform mGluR7 together.

Please try each isoform separately.

mGluR7 Specific Agonists, Antagonists & Modulators
Product Name mGluR7 mGluR8 mGluR6 mGluR5 mGluR4 mGluR3 mGluR2 mGluR1 mGluR7 Selectivity Purity
VU6012962
mGlu7, IC50: 347 nM
              Selective Modulator 99.92%
ADX71743
mGlu7
              Selective Antagonist
LY341495
mGluR7, IC50: 990 nM
mGluR8, IC50: 170 nM
 
mGluR5a, IC50: 8.2 μM
mGluR4, IC50: 22 μM
mGluR3, IC50: 14 nM
mGluR2, IC50: 21 nM
mGluR1a, IC50: 7.8 μM
Pan Antagonist 99.11%
L-APB
mGlu7, EC50: 249 μM
mGlu8, EC50: 0.29 μM
mGlu6, EC50: 1.0 μM
 
mGlu4, EC50: 0.13 μM
      Pan Agonist >99.0%
O-Phospho-L-serine
mGluR7
mGluR8
mGluR6
 
mGluR4
 
mGluR2
mGluR1
Pan Modulator >98.0%
VU6005649
mGlu7 Receptor, EC50: 0.65 μM
mGlu8 Receptor, EC50: 2.6 μM
            Pan Agonist 98.67%
DCG-IV
mGluR7, IC50: 40.1 μM
mGluR8, IC50: 32 μM
mGluR6, IC50: 39.6 μM
mGluR5, IC50: 630 μM
mGluR4R, IC50: 22.5 μM
mGluR3R, EC50: 0.09 μM
mGluR2R, EC50: 0.35 μM
mGluR1R, IC50: 389 μM
Pan Agonist
(RS)-PPG
hmGluR7b, EC50: 185 μM
hmGluR8a, EC50: 0.2 μM
hmGluR6, EC50: 4.7 μM
 
hmGluR4a, EC50: 5.2 μM
      Pan Agonist