407-41-0
407-41-0
Chemical Structure
O-Phospho-L-serine
Synonym(s): L-Serine O-phosphate; L-SOP
- CAS No.: 407-41-0
- Formula:C3H8NO6P
- Molecular Weight:185.07
IUPAC Name: O-phosphono-L-serine
InChIKey: BZQFBWGGLXLEPQ-REOHCLBHSA-N
SMILES: OP(OC[C@@H](C(O)=O)N)(O)=O
Biological Activity: O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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O-Phospho-L-serine | 99.90% | O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. | ||||||||||||||||||||
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O-Phospho-L-serine (Standard) | 97.61% | O-Phospho-L-serine (Standard) (L-Serine O-phosphate (Standard)) is the analytical standard of O-Phospho-L-serine (HY-15129). This product is intended for research and analytical applications. O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8). O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. | ||||||||||||||||||||
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O-Phospho-L-serine-13C3 | O-Phospho-L-serine-13C3 (L-Serine O-phosphate-13C3) is the 13C-labeled O-Phospho-L-serine (HY-15129). O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. | |||||||||||||||||||||
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O-Phospho-L-serine-13C3,15N | O-Phospho-L-serine-13C3,15N is the 13C- and 15N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. | |||||||||||||||||||||
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O-Phospho-L-threonine | 99.89% | O-Phospho-L-threonine is a threonine derivative. | ||||||||||||||||||||
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3-Phosphoglyceric acid | 99.88% | 3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation. | ||||||||||||||||||||
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O-Phospho-D-serine | O-Phospho-D-serine (D-SOP) is the D-configurational enantiomer of O-Phospho-L-serine (HY-15129). O-Phospho-D-serine inhibits L-[3H]glutamate binding to APB-sensitive sites in rat brain synaptic plasma membranes, with a Ki of 303 μM. Compared with the L-configurational form, D-SOP does not significantly activate the tested mGluR at 1 mM, and it is mainly used in studies related to the stereoselectivity of phosphatidylserine and mGluR ligands. |
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DL-O-Phosphoserine | 98.0% | DL-O-Phosphoserine is a normal metabolite in human biofluids and is a mixture of phosphoserine with two stereochemical structures (D-type and L-type O-phospho-serine). O-phospho-L-serine is a competitive inhibitor of serine racemase and phagocytosis. O-phospho-L-serine inhibits the enzymatic reaction by competing with the active site of serine racemase, thereby affecting the production of D-serine. O-phospho-L-serine also mimics the phosphatidylserine head group, binds to the phosphatidylserine receptor, interferes with phagocytic signal transduction, and partially blocks the phagocytosis of apoptotic cells by cells. O-phospho-L-serin can be used in the research of retinal regeneration, bone repair, and insect growth and development. | ||||||||||||||||||||
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β-Aspartyl phosphate | β-Aspartyl phosphate is a nucleoside metabolite. | |||||||||||||||||||||
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3-Phospho-D-glycerate | 3-Phospho-D-glycerate can be converted to 2-phospho-d-glycerate (2-PGA) via phosphoglycerate mutase. | |||||||||||||||||||||
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O-Phosphono-L-homoserine | O-Phosphono-L-homoserine (o-Phosphohomoserine) is an intermediate in threonine synthesis in bacteria and plants, and can also be hijacked by MetM in some Streptomyces species to enter a novel methionine synthesis pathway. O-Phosphono-L-homoserine acts as a weak antagonist of the NMDA receptor. O-Phosphono-L-homoserine can be used as a substrate for studies on amino acid metabolism of the aspartate family, a control for mechanism studies of PLP enzymes, and a reference for structure-activity relationship studies of NMDA receptor ligands. | |||||||||||||||||||||
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O-Phospho-DL-threonine | O-Phospho-DL-threonine is a threonine derivative. | |||||||||||||||||||||
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