1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. mGluR
  4. mGluR6 Inhibitors

mGluR6 Inhibitors

mGluR1

mGluR2

mGluR3

mGluR4

mGluR5

mGluR6

mGluR7

mGluR8

mGluR

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform mGluR6 together.

Please try each isoform separately.

mGluR6 Specific Agonists & Modulators
Product Name mGluR6 mGluR1 mGluR2 mGluR3 mGluR4 mGluR5 mGluR7 mGluR8 mGluR6 Selectivity Purity
L-AP4 monohydrate
mGlu6, EC50: 1.0 μM
     
mGlu4, EC50: 0.13 μM
 
mGlu7, EC50: 249 μM
mGlu8, EC50: 0.29 μM
Pan Agonist ≥99.0%
L-Cysteinesulfinic acid monohydrate
mGluR6, pEC50: 4.0
mGluR1, pEC50: 3.92
mGluR2, pEC50: 3.9
 
mGluR4, pEC50: 2.7
mGluR5, pEC50: 4.6
 
mGluR8, pEC50: 3.94
Pan Agonist 99.30%
VU0364770
mGlu6, EC50: 6.8 μM
     
Rat mGlu4, EC50: 290 nM
Human mGlu4, EC50: 1.1 μM
mGlu5, EC50: 17.9 μM
    Pan Agonist 99.57%
L-AP4
mGlu6, EC50: 1.0 μM
     
mGlu4, EC50: 0.13 μM
 
mGlu7, EC50: 249 μM
mGlu8, EC50: 0.29 μM
Pan Agonist ≥99.0%
O-Phospho-L-serine
mGluR6
mGluR1
mGluR2
 
mGluR4
 
mGluR7
mGluR8
Pan Modulator ≥98.0%
L-Cysteinesulfinic acid
mGluR6, pEC50: 4.0
mGluR1, pEC50: 3.92
mGluR2, pEC50: 3.9
 
mGluR4, pEC50: 2.7
mGluR5, pEC50: 4.6
 
mGluR8, pEC50: 3.94
Pan Agonist
DCG-IV
mGluR6, IC50: 39.6 μM
mGluR1R, IC50: 389 μM
mGluR2R, EC50: 0.35 μM
mGluR3R, EC50: 0.09 μM
mGluR4R, IC50: 22.5 μM
mGluR5, IC50: 630 μM
mGluR7, IC50: 40.1 μM
mGluR8, IC50: 32 μM
Pan Agonist
(RS)-PPG
hmGluR6, EC50: 4.7 μM
     
hmGluR4a, EC50: 5.2 μM
 
hmGluR7b, EC50: 185 μM
hmGluR8a, EC50: 0.2 μM
Pan Agonist
VU0364770 hydrochloride
mGlu6, EC50: 6.8 μM
     
Rat mGlu4, EC50: 290 nM
Human mGlu4, EC50: 1.1 μM
mGlu5, EC50: 17.9 μM
    Pan Agonist 99.82%