1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. mGluR
  4. mGluR6 Inhibitors

mGluR6 Inhibitors

mGluR8

mGluR6

mGluR7

mGluR5

mGluR4

mGluR3

mGluR2

mGluR1

mGluR

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform mGluR6 together.

Please try each isoform separately.

mGluR6 Specific Agonists & Modulators
Product Name mGluR6 mGluR8 mGluR7 mGluR5 mGluR4 mGluR3 mGluR2 mGluR1 mGluR6 Selectivity Purity
L-Cysteinesulfinic acid monohydrate
mGluR6, pEC50: 4.0
mGluR8, pEC50: 3.94
 
mGluR5, pEC50: 4.6
mGluR4, pEC50: 2.7
 
mGluR2, pEC50: 3.9
mGluR1, pEC50: 3.92
Pan Agonist
VU0364770
mGlu6, EC50: 6.8 μM
   
mGlu5, EC50: 17.9 μM
Rat mGlu4, EC50: 290 nM
Human mGlu4, EC50: 1.1 μM
      Pan Agonist 99.57%
L-APB
mGlu6, EC50: 1.0 μM
mGlu8, EC50: 0.29 μM
mGlu7, EC50: 249 μM
 
mGlu4, EC50: 0.13 μM
      Pan Agonist >99.0%
O-Phospho-L-serine
mGluR6
mGluR8
mGluR7
 
mGluR4
 
mGluR2
mGluR1
Pan Modulator >98.0%
L-Cysteinesulfinic acid
mGluR6, pEC50: 4.0
mGluR8, pEC50: 3.94
 
mGluR5, pEC50: 4.6
mGluR4, pEC50: 2.7
 
mGluR2, pEC50: 3.9
mGluR1, pEC50: 3.92
Pan Agonist
DCG-IV
mGluR6, IC50: 39.6 μM
mGluR8, IC50: 32 μM
mGluR7, IC50: 40.1 μM
mGluR5, IC50: 630 μM
mGluR4R, IC50: 22.5 μM
mGluR3R, EC50: 0.09 μM
mGluR2R, EC50: 0.35 μM
mGluR1R, IC50: 389 μM
Pan Agonist
(RS)-PPG
hmGluR6, EC50: 4.7 μM
hmGluR8a, EC50: 0.2 μM
hmGluR7b, EC50: 185 μM
 
hmGluR4a, EC50: 5.2 μM
      Pan Agonist
VU0364770 hydrochloride
mGlu6, EC50: 6.8 μM
   
mGlu5, EC50: 17.9 μM
Rat mGlu4, EC50: 290 nM
Human mGlu4, EC50: 1.1 μM
      Pan Agonist 99.82%