mGluR7 antagonist-2
mGluR7 antagonist-2 (compound 1) is a potent and selective metabotropic glutamate receptor 7 (mGluR7) allosteric antagonist (IC50 = 20 nM). mGluR7 antagonist-2 shows high selectivity over other mGluRs (mGluR1/2/3/4/5/6/8).
For research use only. We do not sell to patients.
- CAS No.: 60986-80-3
- Formula: C19H14N2O2
- Molecular Weight:302.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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mGlu7 20 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
20 nM
Compound: 1
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Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR
Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPR
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[PMID: 20005101] |
Chemical Information
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CAS No. 60986-80-3
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Molecular Weight 302.33
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Formula C19H14N2O2
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SMILES
O=C1C2=C(C=C(N1C)C3=CC=CC=C3)ON=C2C4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
mGluR7 antagonist-2 Related Classifications
HY-128099 Related Classifications
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