1. GPCR/G Protein
    Neuronal Signaling
  2. mGluR
  3. VU0422288

VU0422288 (Synonyms: ML396)

Cat. No.: HY-110190
Handling Instructions

VU0422288 is a positive allosteric modulator of group III mGluRs with EC50 values of 108, 146, and 128 nM for mGluR4, mGluR7, and mGluR8, respectively in calcium mobilization assays.

For research use only. We do not sell to patients.

VU0422288 Chemical Structure

VU0422288 Chemical Structure

CAS No. : 1630936-95-6

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Description

VU0422288 is a positive allosteric modulator of group III mGluRs with EC50 values of 108, 146, and 128 nM for mGluR4, mGluR7, and mGluR8, respectively in calcium mobilization assays[1].

IC50 & Target

mGluR4

108 nM (EC50)

mGluR7

146 nM (EC50)

mGluR8

128 nM (EC50)

Molecular Weight

360.19

Formula

C17H11Cl2N3O2

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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VU0422288
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HY-110190
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