1. GPCR/G Protein
  2. mGluR

VU6012962 

Cat. No.: HY-114403
Handling Instructions

VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate receptor 7 (mGlu7) negative allosteric modulator (NAM) with an IC50 of 347 nM.

For research use only. We do not sell to patients.

VU6012962 Chemical Structure

VU6012962 Chemical Structure

Size Stock
250 mg Get quote
500 mg Get quote

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  • References

Description

VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate receptor 7 (mGlu7) negative allosteric modulator (NAM) with an IC50 of 347 nM[1].

IC50 & Target

IC50: 347 nM (mGlu7)[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2302 mL 11.1508 mL 22.3015 mL
5 mM 0.4460 mL 2.2302 mL 4.4603 mL
10 mM 0.2230 mL 1.1151 mL 2.2302 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

448.40

Formula

C₂₁H₁₉F₃N₄O₄

SMILES

O=C(C1=CC=C(OCC2CC2)C(OC)=C1)NC3=C(N4C=NC=N4)C=CC(OC(F)(F)F)=C3

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
VU6012962
Cat. No.:
HY-114403
Quantity:

VU6012962

Cat. No.: HY-114403