1. GPCR/G Protein
    Neuronal Signaling
  2. mGluR
  3. DHPG

DHPG (Synonyms: (RS)-3,5-DHPG)

Cat. No.: HY-12598A Purity: >97.0%
Handling Instructions

DHPG ((RS)-3,5-DHPG) is an amino acid, which acts as a selective and potent agonist of group I mGluR (mGluR 1 and mGluR 5), shows no effect on Group II or Group III mGluRs. DHPG ((RS)-3,5-DHPG) is also an effective antagonist of mGluRs linked to phospholipase D.

For research use only. We do not sell to patients.

DHPG Chemical Structure

DHPG Chemical Structure

CAS No. : 146255-66-5

Size Price Stock Quantity
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 80 In-stock
Estimated Time of Arrival: December 31
50 mg USD 280 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

DHPG ((RS)-3,5-DHPG) is an amino acid, which acts as a selective and potent agonist of group I mGluR (mGluR 1 and mGluR 5), shows no effect on Group II or Group III mGluRs[1]. DHPG ((RS)-3,5-DHPG) is also an effective antagonist of mGluRs linked to phospholipase D[2].

IC50 & Target[1]

mGluR 1

 

mGluR 5

 

Molecular Weight

183.16

Formula

C₈H₉NO₄

CAS No.

146255-66-5

SMILES

O=C(O)C(N)C1=CC(O)=CC(O)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 1 mg/mL (5.46 mM; Need ultrasonic)

DMSO : 1 mg/mL (5.46 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4597 mL 27.2985 mL 54.5971 mL
5 mM 1.0919 mL 5.4597 mL 10.9194 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
References
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DHPG
Cat. No.:
HY-12598A
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