441765-98-6
Chemical Structure
Talaglumetad
Synonym(s): LY-544344
- CAS No.: 441765-98-6
- Formula:C11H16N2O5
- Molecular Weight:256.26
IUPAC Name: (1S,2S,5R,6S)-2-((S)-2-aminopropanamido)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
InChIKey: UPSXYNJDCKOCFD-QIMCWZKGSA-N
SMILES: C[C@H](N)C(N[C@@]1([C@@]2([H])[C@](CC1)([H])[C@@H]2C(O)=O)C(O)=O)=O
Biological Activity: Talaglumetad (LY-544344) is an orally active prodrug of Eglumegad (HY-18941) and a metabotropic glutamate receptor 2/3 (mGluR2/3) agonist. Talaglumetad undergoes transmembrane transport via the intestinal peptide transporter hPepT1, and is enzymatically hydrolyzed to produce L-alanine and the parent drug Eglumegad after entering the body. Talaglumetad can be used in research related to metabotropic glutamate receptor 2-associated neurological systems[1][2].
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Talaglumetad | Talaglumetad (LY-544344) is an orally active prodrug of Eglumegad (HY-18941) and a metabotropic glutamate receptor 2/3 (mGluR2/3) agonist. Talaglumetad undergoes transmembrane transport via the intestinal peptide transporter hPepT1, and is enzymatically hydrolyzed to produce L-alanine and the parent drug Eglumegad after entering the body. Talaglumetad can be used in research related to metabotropic glutamate receptor 2-associated neurological systems. | |||||||||||||||||||||
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Keywords
