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  3. FD-1080

FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging.

For research use only. We do not sell to patients.

FD-1080 Chemical Structure

FD-1080 Chemical Structure

CAS No. : 1151666-58-8

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Description

FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging[1].

In Vitro

FD-1080 shows superior photostability under the continuous laser irradiation. The quantum yield of FD-1080 is 0.31%, and can be increased to 5.94% after combining with fetal bovine serum (FBS) to form FD-1080-FBS complexes[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

The 1064 nm NIR-II excitation of FD-1080 is demonstrated with the high tissue penetration depth and superior imaging resolution compared to NIR excitation from 650 nm to 980 nm. Deeptissue and high-resolution in vivo imaging for the left hindlimb vasculature, abdomen, and brain vessels was realized, allowing penetration through intact skin, tissue, and skull. FD-1080 also quantifying the respiratory rate based on the dynamic imaging of respiratory craniocaudal motion of the liver for the awake and anaesthetized mouse[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

765.31

Formula

C40H38ClN2NaO6S2

CAS No.
Appearance

Solid

Color

Brown to black

Emission (Em)

1000

Excitation (Ex)

985

SMILES

O=S(CCCC[N+]1=C(/C=C/C2=C(Cl)/C(CCC2)=C/C=C3N(CCCCS(=O)(O[Na])=O)C4=C5C\3=CC=CC5=CC=C4)C6=CC=CC7=C6C1=CC=C7)([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
Dyeing Example
References
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FD-1080 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FD-1080
Cat. No.:
HY-133852
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