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  2. FD-1080

FD-1080 

Cat. No.: HY-133852
Handling Instructions

FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging.

For research use only. We do not sell to patients.

FD-1080 Chemical Structure

FD-1080 Chemical Structure

CAS No. : 1151666-58-8

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Description

FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging[1].

In Vitro

FD-1080 shows superior photostability under the continuous laser irradiation. The quantum yield of FD-1080 is 0.31%, and can be increased to 5.94% after combining with fetal bovine serum (FBS) to form FD-1080-FBS complexes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

The 1064 nm NIR-II excitation of FD-1080 is demonstrated with the high tissue penetration depth and superior imaging resolution compared to NIR excitation from 650 nm to 980 nm. Deeptissue and high-resolution in vivo imaging for the left hindlimb vasculature, abdomen, and brain vessels was realized, allowing penetration through intact skin, tissue, and skull. FD-1080 also quantifying the respiratory rate based on the dynamic imaging of respiratory craniocaudal motion of the liver for the awake and anaesthetized mouse[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

765.31

Formula

C₄₀H₃₈ClN₂NaO₆S₂

CAS No.

1151666-58-8

SMILES

O=S(CCCC[N+]1=C(/C=C/C2=C(Cl)/C(CCC2)=C/C=C3N(CCCCS(=O)(O[Na])=O)C4=C5C\3=CC=CC5=CC=C4)C6=CC=CC7=C6C1=CC=C7)([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

FD-1080FD1080FD 1080OthersNIR-IIregionorganicdyevivoimagingvesselsInhibitorinhibitorinhibit

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FD-1080
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HY-133852
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