2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topoisomerase II inhibitor 5

Topoisomerase II inhibitor 5 (Compound E24) is a DNA topoisomerase II inhibitor with anticancer activities.

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Topoisomerase II inhibitor 5

Topoisomerase II inhibitor 5 Chemical Structure

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Topoisomerase II inhibitor 5 Related Antibodies

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Description

Topoisomerase II inhibitor 5 (Compound E24) is a DNA topoisomerase II inhibitor with anticancer activities[1].

IC50 & Target

Topoisomerase II

 

In Vitro

Topoisomerase II inhibitor 5 (Compound E24) (0-20 μM, 72 h) shows antiproliferative activities against cancer cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Topoisomerase II inhibitor 5 Related Antibodies

Cell Proliferation Assay[1]

Cell Line: SW480, HCT116 and HeLa
Concentration: 0-20 μM
Incubation Time: 72 h
Result: Showed antiproliferative activities with IC50 values of 1.2 ± 0.3, 0.7 ± 0.05 and 1.2 ± 0.04 μM against SW480, HCT116 and HeLa cells, respectively.
Masse moléculaire

473.52

Formule

C26H27N5O4
SMILES

O=C1C2=C(C([N+]([O-])=O)=CC=C2NC3=CC=C(CCN4CCN(C)CC4)C=C3)NC5=C1C=C(O)C=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Topoisomerase II inhibitor 5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerase II inhibitor 5Topoisomerase II inhibitor5Topoisomerase II inhibitor-5TopoisomeraseanticancerSW480HCT116HeLaInhibitorinhibitorinhibit

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Topoisomerase II inhibitor 5
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HY-143281
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