2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. von Willebrand Factor Antibody (YA2406)

von Willebrand Factor Antibody (YA2406)

Art. -Nr.: HY-P82661
COA
SDS
User Guide for Antibodies Technical Support

von Willebrand Factor Antibody (YA2406) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to von Willebrand Factor.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Beschreibung

Beschreibung

von Willebrand Factor Antibody (YA2406) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to von Willebrand Factor.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Molekulargewicht
Predicted band size: 309 kDa;
Observed band size: 309 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Rat
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human Von Willebrand Factor
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
Sensitivity Endogenous Reinheit Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Versand

Shipping with blue ice.
Background
Function：Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma
Subcellular Localization：Secreted; Secreted, extracellular space, extracellular matrix
Expression：
Tissue_specificity:plasma
Isoforms & Post-Translational Modification：P04275 has 2 isomers: P04275-1: 309265 Da (predicted); P04275-2: 38745 Da (predicted).
All cysteine residues are involved in intrachain or interchain disulfide bonds;N- and O-glycosylated
Subunit：Multimeric. Interacts with F8
RRID
Database

Entrez Gene: 116669 Rat

SwissProt: Q62935 

Research Field

Cardiovascular
Synonyms
VWF; von Willebrand factor; von Willebrand antigen II; F8VWF
Dokumentation
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

von Willebrand Factor Antibody (YA2406) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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von Willebrand Factor Antibody (YA2406)
Art. -Nr.:
HY-P82661
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SAFETY DATA SHEET (SDS)

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