1. Metabolic Enzyme/Protease
  2. Proteasome
  3. (Rac)-Calpain Inhibitor XII

(Rac)-Calpain Inhibitor XII 

Cat. No.: HY-116171
Handling Instructions

(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM), with lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.

For research use only. We do not sell to patients.

(Rac)-Calpain Inhibitor XII Chemical Structure

(Rac)-Calpain Inhibitor XII Chemical Structure

CAS No. : 181769-57-3

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Description

(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain, Ki=19 nM), with lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has been used to study the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury.

Molecular Weight

482.57

Formula

C₂₆H₃₄N₄O₅

CAS No.

181769-57-3

SMILES

O=C(OCC1=CC=CC=C1)NC(C(NC(C(C(NCC2=NC=CC=C2)=O)=O)CCC)=O)CC(C)C

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Keywords:

(Rac)-Calpain Inhibitor XIIProteasomeInhibitorinhibitorinhibit

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(Rac)-Calpain Inhibitor XII
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