1. Metabolic Enzyme/Protease
  2. Proteasome

PD150606 

Cat. No.: HY-100529 Purity: >98.0%
Handling Instructions

PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor (Ki values for ν and m-calpains are 0.21 and 0.37 μM respectively).

For research use only. We do not sell to patients.

PD150606 Chemical Structure

PD150606 Chemical Structure

CAS No. : 179528-45-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 79 In-stock
Estimated Time of Arrival: December 31
5 mg USD 72 In-stock
Estimated Time of Arrival: December 31
10 mg USD 132 In-stock
Estimated Time of Arrival: December 31
25 mg USD 276 In-stock
Estimated Time of Arrival: December 31
50 mg USD 492 In-stock
Estimated Time of Arrival: December 31
100 mg USD 888 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor (Ki values for ν and m-calpains are 0.21 and 0.37 μM respectively). target:calpain[1] In vitro: PD150606 also against tetrafluoroethyl-l-cysteine-, bromohydroquinone-, oxidant (t-butylhydroperoxide)- and calcium ionophore (ionomycin)-induced cell death. PD150606 inhibits calpains by binding to the calcium-binding domain of the enzyme. [2] high specificity for calpains relative to other proteases, uncompetitive inhibition with respect to substrate.[3]

Solvent & Solubility
In Vitro: 

DMSO : ≥ 28 mg/mL (91.47 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2667 mL 16.3335 mL 32.6669 mL
5 mM 0.6533 mL 3.2667 mL 6.5334 mL
10 mM 0.3267 mL 1.6333 mL 3.2667 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

306.12

Formula

C₉H₇IO₂S

CAS No.

179528-45-1

SMILES

O=C(O)/C(S)=C/C1=CC=C(I)C=C1

Storage

4°C, protect from light

Shipping

Room temperature in continental US; may vary elsewhere

Purity: >98.0%

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
PD150606
Cat. No.:
HY-100529
Quantity:

PD150606

Cat. No.: HY-100529