Urotensin II-related peptide
Based on 1 Customer Validation
Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor.
For research use only. We do not sell to patients.
- Purity : 99.52%
- CAS No.: 342878-90-4
- Formula: C49H64N10O10S2
- Molecular Weight:1017.22
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-10664
SB-611812Urotensin Receptor Antagonist -
HY-10655
PalosuranUrotensin II Antagonist -
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GSK 1562590 hydrochlorideUrotensin-II Receptor Antagonist -
HY-10657
SB-706375Urotensin II Receptor Antagonist -
HY-P1164
Urotensin II (114-124), humanUrotensin Receptor Agonist -
HY-10664R
SB-611812 (Standard)Urotensin Receptor Antagonist -
HY-10658
AC-7954Urotensin Receptor Agonist -
HY-10657R
SB-706375 (Standard)Reference Standard -
HY-10656
SB-657510UII Receptor Antagonist -
HY-10656R
SB-657510 (Standard)Reference Standard -
![[Orn8]-Urotensin II (human)](https://file.medchemexpress.com/product_pic/hy-p1168.gif)
HY-P1168
[Orn8]-Urotensin II (human)UT Receptor Agonist -
HY-P1166
UFP-803UT Antagonist
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
12 nM
Compound: 2, URP
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Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis
Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis
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[PMID: 24251366] |
Chemical Information
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CAS No. 342878-90-4
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Appearance Solid
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Molecular Weight 1017.22
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Formula C49H64N10O10S2
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Color White to off-white
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Sequence
Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge:Cys2-Cys7)
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Sequence Shortening
ACFWKYCV (Disulfide bridge:Cys2-Cys7)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (98.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Lescot E, et al. Nonpeptide Urotensin-II receptor agonists and antagonists: Review and structure–activity relationships Peptides. 2008 May;29(5):680-90. [Content Brief]
[2]. Labarrère P, et al. Structure-activity relationships of human urotensin II and related analogues on rat aortic ring contraction. J Enzyme Inhib Med Chem. 2003 Apr;18(2):77-88. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9831 mL | 4.9154 mL | 9.8307 mL | 24.5768 mL |
| 5 mM | 0.1966 mL | 0.9831 mL | 1.9661 mL | 4.9154 mL | |
| 10 mM | 0.0983 mL | 0.4915 mL | 0.9831 mL | 2.4577 mL | |
| 15 mM | 0.0655 mL | 0.3277 mL | 0.6554 mL | 1.6385 mL | |
| 20 mM | 0.0492 mL | 0.2458 mL | 0.4915 mL | 1.2288 mL | |
| 25 mM | 0.0393 mL | 0.1966 mL | 0.3932 mL | 0.9831 mL | |
| 30 mM | 0.0328 mL | 0.1638 mL | 0.3277 mL | 0.8192 mL | |
| 40 mM | 0.0246 mL | 0.1229 mL | 0.2458 mL | 0.6144 mL | |
| 50 mM | 0.0197 mL | 0.0983 mL | 0.1966 mL | 0.4915 mL | |
| 60 mM | 0.0164 mL | 0.0819 mL | 0.1638 mL | 0.4096 mL | |
| 80 mM | 0.0123 mL | 0.0614 mL | 0.1229 mL | 0.3072 mL |
Urotensin II-related peptide Related Classifications
HY-P1165 Related Classifications
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