2. GPCR/G Protein
  3. Urotensin Receptor
  4. Urotensin II, mouse TFA

Urotensin II, mouse TFA 

Cat. No.: HY-P1483A Purity: 99.58%
COA Handling Instructions

Urotensin II, mouse TFA is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse TFA is a potent vasoconstrictor. Urotensin II, mouse TFA plays a physiological role in the central nervous system.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Urotensin II, mouse TFA Chemical Structure

Urotensin II, mouse TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 180 In-stock
Estimated Time of Arrival: December 31
5 mg USD 720 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Urotensin II, mouse TFA is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse TFA is a potent vasoconstrictor. Urotensin II, mouse TFA plays a physiological role in the central nervous system[1].

IC50 & Target

GPR14[1]
In Vivo

Urotensin II is a somatostatin-like cyclic peptide which functions as an arterial vasocontrictor, vasodilator, and bronchoconstriction mediator[1].
Urotensin II (0.1 nmol, 0.3 nmol, and 3 nmol; intracerebroventricular administration) induces anxiogenic-like behaviors in the elevated plus maze test and the hole-board test in mice in a dose-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male C57BL/6N mice (8 weeks old)[1]
Dosage: 0.1 nmol, 0.3 nmol, and 3 nmol
Administration: Intracerebroventricular (i.c.v.) administration
Result: Decreased the amount of head dipping without significant alteration of the motor activity.
Molecular Weight

1747.88

Appearance

Solid

Formula

C78H101N18F3O21S2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (28.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5721 mL 2.8606 mL 5.7212 mL
5 mM 0.1144 mL 0.5721 mL 1.1442 mL
10 mM 0.0572 mL 0.2861 mL 0.5721 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (57.21 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.58%

COA (243 KB) LCMS (112 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Keywords:

Urotensin II, mouseUrotensin ReceptorUT receptorendogenousligandSENRcentralnervoussystemVasoconstrictorInhibitorinhibitorinhibit

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