Secretogranin-2 Protein, Human (HEK293, His)
Secretogranin-2 Protein, a neuroendocrine member of the granin family, orchestrates the biogenesis of secretory granules, playing a pivotal role in their formation and maturation. It interacts with Secretogranin III/SCG3, highlighting its engagement in dynamic molecular networks crucial for finely tuned mechanisms in secretory granule development and function. Secretogranin-2 Protein, Human (HEK293, His) is the recombinant human-derived Secretogranin-2 protein, expressed by HEK293 , with C-6*His labeled tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
Secretogranin-2 Protein, a neuroendocrine member of the granin family, orchestrates the biogenesis of secretory granules, playing a pivotal role in their formation and maturation. It interacts with Secretogranin III/SCG3, highlighting its engagement in dynamic molecular networks crucial for finely tuned mechanisms in secretory granule development and function. Secretogranin-2 Protein, Human (HEK293, His) is the recombinant human-derived Secretogranin-2 protein, expressed by HEK293 , with C-6*His labeled tag.
Background
Secretogranin-2, a neuroendocrine protein belonging to the granin family, plays a pivotal role in orchestrating the biogenesis of secretory granules. Its regulatory influence is integral to the intricate processes governing the formation and maturation of these specialized cellular compartments. Notably, Secretogranin-2 engages in interactions with Secretogranin III/SCG3, underscoring its participation in dynamic molecular networks that contribute to the finely tuned mechanisms of secretory granule development and function.
Technical Parameters
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Species Human
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Source HEK293
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Tag C-6*His
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Accession
P13521 (S29-M617)
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Molecular Construction
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N-term
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Secretogranin-2 (S29-M617)
Accession # P13521 -
6*His
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C-term
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Protein Length
Full Length of Secretogranin-2 Chain
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Synonyms
SCG2; SN; Secretogranin II; Chromogranin-C; CHGC; Secretoneurin; SgII; Chromogranin C; Secretogranin-2; EM66
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AA Sequence
SFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIENLRQQAHKEESSPDYNPYQGVSVPLQQKENGDESHLPERDSLSEEDWMRIILEALRQAENEPQSAPKENKPYALNSEKNFPMDMSDDYETQQWPERKLKHMQFPPMYEENSRDNPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERMDEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENIEKNEQINDEMKRSGQLGIQEEDLRKESKDQLSDDVSKVIAYLKRLVNAAGSGRLQNGQNGERATRLFEKPLDSQSIYQLIEISRNLQIPPEDLIEMLKTGEKPNGSVEPERELDLPVDLDDISEADLDHPDLFQNRMLSKSGYPKTPGRAGTEALPDGLSVEDILNLLGMESAANQKTSYFPNPYNQEKVLPRLPYGAGRSRSNQLPKAAWIPHVENRQMAYENLNDKDQELGEYLARMLVKYPEIINSNQVKRVPGQGSSEDDLQEEEQIEQAIKEHLNQGSSQETDKLAPVSKRFPVGPPKNDDTPNRQYWDEDLLMKVLEYLNQEKAEKGREHIAKRAMENM
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Predicted Molecular Mass
68.9 kDa
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Molecular Weight
Approximately 85-95 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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