Candesartan-d4
Based on 1 Customer Validation
Candesartan-d4 (CV-11974-d4) is the deuterium labeled Candesartan (HY-B0205). Candesartan (CV 11974) is an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. Candesartan has potent and long-lasting antihypertensive effects. Candesartan can be used for the research of hypertension, chronic heart failure (CHF) and Traumatic brain injury (TBI).
For research use only. We do not sell to patients.
- Purity: 98.17%
- CAS No.: 1346604-70-3
- Formula: C24H16D4N6O3
- Molecular Weight:444.48
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All Angiotensin Receptor Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1346604-70-3
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Unlabeled Cas 139481-59-7
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Appearance Solid
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Molecular Weight 444.48
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Formula C24H16D4N6O3
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Color White to off-white
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SMILES
[2H]C1=C(CN2C(C(C(O)=O)=CC=C3)=C3N=C2OCC)C([2H])=C([2H])C(C4=CC=CC=C4C5=NNN=N5)=C1[2H]
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Synonyms
CV-11974-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 30 mg/mL (67.49 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
DMF : ≥ 30 mg/mL (67.49 mM)
Ethanol : ≥ 3 mg/mL (6.75 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (254 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO / DMF | 1 mM | 2.2498 mL | 11.2491 mL | 22.4982 mL | 56.2455 mL |
| 5 mM | 0.4500 mL | 2.2498 mL | 4.4996 mL | 11.2491 mL | |
| DMSO / DMF | 10 mM | 0.2250 mL | 1.1249 mL | 2.2498 mL | 5.6245 mL |
| 15 mM | 0.1500 mL | 0.7499 mL | 1.4999 mL | 3.7497 mL | |
| 20 mM | 0.1125 mL | 0.5625 mL | 1.1249 mL | 2.8123 mL | |
| 25 mM | 0.0900 mL | 0.4500 mL | 0.8999 mL | 2.2498 mL | |
| 30 mM | 0.0750 mL | 0.3750 mL | 0.7499 mL | 1.8748 mL | |
| 40 mM | 0.0562 mL | 0.2812 mL | 0.5625 mL | 1.4061 mL | |
| 50 mM | 0.0450 mL | 0.2250 mL | 0.4500 mL | 1.1249 mL | |
| 60 mM | 0.0375 mL | 0.1875 mL | 0.3750 mL | 0.9374 mL |
Candesartan-d4 Related Classifications
HY-B0205S Related Classifications
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