1. Anti-infection
  2. Fungal
  3. Filipin complex

Filipin complex 

Cat. No.: HY-N6716 Purity: >97.0%
Handling Instructions

Filipin, produced as a mixture of related compounds known as the filipin complex (filipins I-IV) in nature, is a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure. Filipin III is the major component of Filipin.

For research use only. We do not sell to patients.

Filipin complex Chemical Structure

Filipin complex Chemical Structure

CAS No. : 11078-21-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 86 In-stock
Estimated Time of Arrival: December 31
5 mg USD 60 In-stock
Estimated Time of Arrival: December 31
10 mg USD 95 In-stock
Estimated Time of Arrival: December 31
50 mg USD 280 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Filipin, produced as a mixture of related compounds known as the filipin complex (filipins I-IV) in nature[1], is a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure. Filipin III is the major component of Filipin[2].

Molecular Weight

654.80

Formula

C₃₅H₅₈O₁₁ (for Filipin III)

CAS No.

11078-21-0

SMILES

[Filipin complex]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (152.72 mM)

Ethanol : 25 mg/mL (38.18 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5272 mL 7.6359 mL 15.2718 mL
5 mM 0.3054 mL 1.5272 mL 3.0544 mL
10 mM 0.1527 mL 0.7636 mL 1.5272 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (3.82 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (3.82 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (3.82 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: >97.0%

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KeyWords:

Filipin complex | Fungal | Inhibitor | inhibitor | inhibit

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Product name:
Filipin complex
Cat. No.:
HY-N6716
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