1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. PAK

PAK-IN-1 

Cat. No.: HY-12632
Handling Instructions

PAK-IN-1 is a PAK inhibitor that displays group II selectivity. PAK-IN-1 inhibits PAK4, PAK5 and PAK6 with IC50s of 7.5, 36, 126 nM, respectively.

For research use only. We do not sell to patients.

PAK-IN-1 Chemical Structure

PAK-IN-1 Chemical Structure

CAS No. : 1394121-05-1

Size Stock
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Featured Recommendations

View All PAK Isoform Specific Products:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

PAK-IN-1 is a PAK inhibitor that displays group II selectivity. PAK-IN-1 inhibits PAK4, PAK5 and PAK6 with IC50s of 7.5, 36, 126 nM, respectively.

IC50 & Target

IC50: 7.5 nM (PAK4), 36 nM (PAK5), 126 nM (PAK6)[1]

In Vitro

PAK-IN-1 is compound 4 from the reference[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4601 mL 12.3007 mL 24.6015 mL
5 mM 0.4920 mL 2.4601 mL 4.9203 mL
10 mM 0.2460 mL 1.2301 mL 2.4601 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

406.48

Formula

C₂₂H₂₆N₆O₂

CAS No.

1394121-05-1

SMILES

OC1(C#CC2=CC=C3N=C(NCCOC)N(C4=NC(N)=NC=C4)C3=C2)CCCCC1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PAK-IN-1
Cat. No.:
HY-12632
Quantity:

PAK-IN-1

Cat. No.: HY-12632