1. Metabolic Enzyme/Protease
  2. Stearoyl-CoA Desaturase (SCD)
  3. SCD1 inhibitor-3

SCD1 inhibitor-3 

Cat. No.: HY-139077
Handling Instructions

SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II diabetes and dyslipidemia, as well as skin diseases, acne and cancer.

For research use only. We do not sell to patients.

SCD1 inhibitor-3 Chemical Structure

SCD1 inhibitor-3 Chemical Structure

CAS No. : 1282606-48-7

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Description

SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II diabetes and dyslipidemia, as well as skin diseases, acne and cancer[1].

IC50 & Target

SCD1[1]

In Vivo

SCD1 inhibitor-3 (5 mg/kg; p.o.; 4 hours) reduces the plasma C16:1/C16:0 triglycerides desaturation index by 54 %[1].
SCD1 inhibitor-3 (2~10 mg/kg; p.o.; 4 hours) makes a dose-responsive reduction of plasma triglycerides desaturation index[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Lewis rats
Dosage: 5 mg/kg
Administration: P.o.; 4 hours
Result: Reduced the plasma C16:1/C16:0 triglycerides desaturation index by 54 %.
Animal Model: Lewis rats
Dosage: 2~10 mg/kg
Administration: P.o.; 4 hours
Result: A dose-responsive reduction of plasma triglycerides desaturation index.
Molecular Weight

393.37

Formula

C₁₉H₁₆FN₇O₂

CAS No.
SMILES

O=C(C1=NNC(N2C=NN(CC3=CC=C(F)C=C3)C2=O)=C1)NCC4=CC=CN=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

SCD1 inhibitor-3Stearoyl-CoA Desaturase (SCD)DiabetesDyslipidemiaSkinAcneCancerSafePotentOralInhibitorinhibitorinhibit

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SCD1 inhibitor-3
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HY-139077
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