Acne
Acne is a common skin condition characterized by clogged hair follicles due to excess oil and dead skin cells, resulting in various lesions such as whiteheads, blackheads, pustules, and cysts. It primarily affects the face, neck, back, chest, and shoulders, with a high prevalence among teenagers and young adults, although it can occur at any age. While not life-threatening, acne can cause scarring and significantly impact self-esteem and mental health, potentially leading to anxiety, low self-confidence, or depression. Hormonal fluctuations, particularly during puberty and pregnancy, are key contributing factors, though diet, cleanliness, and stress do not directly cause acne. Treatment involves gentle skincare, topical or oral medications, and sun protection, aiming to reduce inflammation, prevent new breakouts, and minimize long-term complications.
References:
- [1]. Acne. diseasedb.
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Acne (2)
PF-07905428
Cat. No.: HY-189391
CAS No.: 3027705-65-0
- Formula: C27H34N4O3S
- Molecular Weight: 494.65
PF-07905428 is a topical acetyl-CoA carboxylase (ACC) inhibitor designed to minimize systemic exposure. PF-07905428 inhibits ACC, reduces sebaceous lipid production in the skin. PF-07905428 can be used for the research of acne vulgaris.
(Z)-Broparestrol
Cat. No.: HY-187157
CAS No.: 22393-63-1
- Formula: C22H19Br
- Molecular Weight: 363.29
(Z)-Broparestrol is a prostaglandin synthetase inhibitor with an IC50 of 7.0 μM in cattle. (Z)-Broparestrol inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes. (Z)-Broparestrol is applicable for acne-related research.
