(Z)-Broparestrol
(Z)-Broparestrol is a prostaglandin synthetase inhibitor with an IC50 of 7.0 μM in cattle. (Z)-Broparestrol inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes. (Z)-Broparestrol is applicable for acne-related research.
For research use only. We do not sell to patients.
- CAS No.: 22393-63-1
- Formula: C22H19Br
- Molecular Weight:363.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 22393-63-1
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Molecular Weight 363.29
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Formula C22H19Br
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SMILES
Br/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)\C3=CC=C(C=C3)CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gilbert J, et al. Inhibition of prostaglandin synthetase by di- and triphenylethylene derivatives: a structure-activity study. Journal of medicinal chemistry. 1983 May;26(5):693-9. [Content Brief]
[2]. Toscani S, et al. Overt and hidden polymorphism in the binary system involving the Z- and E- isomers of broparestrol. Int J Pharm. 2025 Jan 25;669:125060. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)