22393-63-1
22393-63-1
Chemical Structure
(Z)-Broparestrol
- CAS No.: 22393-63-1
- Formula:C22H19Br
- Molecular Weight:363.29
IUPAC Name: (Z)-(1-bromo-2-(4-ethylphenyl)ethene-1,2-diyl)dibenzene
InChIKey: OQCYTSHIQNPJIC-DQRAZIAOSA-N
SMILES: Br/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)\C3=CC=C(C=C3)CC
Biological Activity: (Z)-Broparestrol is a prostaglandin synthetase inhibitor with an IC50 of 7.0 μM in cattle. (Z)-Broparestrol inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes. (Z)-Broparestrol is applicable for acne-related research[1][2].
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(Z)-Broparestrol | (Z)-Broparestrol is a prostaglandin synthetase inhibitor with an IC50 of 7.0 μM in cattle. (Z)-Broparestrol inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes. (Z)-Broparestrol is applicable for acne-related research. | |||||||||||||||||||||
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References
- [1]. Gilbert J, et al. Inhibition of prostaglandin synthetase by di- and triphenylethylene derivatives: a structure-activity study. Journal of medicinal chemistry. 1983 May;26(5):693-9. [Content Brief]
- [2]. Toscani S, et al. Overt and hidden polymorphism in the binary system involving the Z- and E- isomers of broparestrol. Int J Pharm. 2025 Jan 25;669:125060. [Content Brief]
Keywords
