1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Adipokinetic hormone II (Locusta migratoria)

Adipokinetic hormone II (Locusta migratoria)  (Synonyms: Lom-AKH-II)

Cat. No.: HY-P3570
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Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs).

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Adipokinetic hormone II (Locusta migratoria) Chemical Structure

Adipokinetic hormone II (Locusta migratoria) Chemical Structure

CAS No. : 98968-94-6

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Description

Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs)[1][3].

In Vitro

Adipokinetic hormone II (Locusta migratoria) (radiolabeled; 1 pmol in 10 μL of 10% methanol; 30 min on ice, and repeated for 2 h at 30 ℃) shows no association with one of the larger protein components, indicating a lack of separate transporting or carrier protein in the hemolymph[1].
Adipokinetic hormones (AKHs) are known to be involved in insect immunity and shows the mechanism of metabolic stimulation, leading a significant increase in carbon dioxide production, and efficacy increase of toxins produced by I. fumosorosea in the cockroach's body[2].
Adipokinetic hormone II is more effective than hormone I in bringing about an accumulation of cAMP in the fat body[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Adipokinetic hormone II (Locusta migratoria) (1 pmol in 10 μL of 10% methanol; injection) plays its own biol. role in the overall syndrome of insect flight, with different half-lives of 40 min and 37 min during rest and flight, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

903.98

Formula

C43H57N11O11

CAS No.
Sequence Shortening

{Glp}-LNFSAGW-NH2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Adipokinetic hormone II (Locusta migratoria) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Adipokinetic hormone II (Locusta migratoria)
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HY-P3570
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