98968-94-6
Chemical Structure
Adipokinetic hormone II (Locusta migratoria)
Synonym(s): Lom-AKH-II
- CAS No.: 98968-94-6
- Formula:C43H57N11O11
- Molecular Weight:903.98
IUPAC Name: 4,7-bis(5-bromothiophen-2-yl)-2-(2-ethylhexyl)-5,6-difluoro-2H-benzo[d][1,2,3]triazole
InChIKey: KMVRKMSUXFKTDO-RKNQSKIKSA-N
SMILES: O=C([C@H]1NC(CC1)=O)N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CO)C(N[C@@H](C)C(NCC(N[C@H](C(N)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O
Biological Activity: Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs)[1][3].
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Adipokinetic hormone II (Locusta migratoria) | 99.58% | Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs). | ||||||||||||||||||||
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- [1]. Oudejans RC, et al. Locust adipokinetic hormones: carrier-independent transport and differential inactivation at physiological concentrations during rest and flight. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8654-9. [Content Brief]
- [3]. Vroemen SF, et al. Stimulation of glycogenolysis by three locust adipokinetic hormones involves Gs and cAMP. Mol Cell Endocrinol. 1995 Feb;107(2):165-71. [Content Brief]
