DPP2 Protein, Human (HEK293, His)
Based on 1 Customer Validation
The DPP2 protein is a key member of the dipeptidyl peptidase family and plays a crucial role in the degradation of specific oligopeptides. It hydrolyzes oligopeptide bonds and promotes the breakdown of peptides into amino acids, emphasizing its importance in the regulation of cellular catabolism and peptide metabolism. DPP2 Protein, Human (HEK293, His) is the recombinant human-derived DPP2 protein, expressed by HEK293 , with C-His labeled tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
The DPP2 protein is a key member of the dipeptidyl peptidase family and plays a crucial role in the degradation of specific oligopeptides. It hydrolyzes oligopeptide bonds and promotes the breakdown of peptides into amino acids, emphasizing its importance in the regulation of cellular catabolism and peptide metabolism. DPP2 Protein, Human (HEK293, His) is the recombinant human-derived DPP2 protein, expressed by HEK293 , with C-His labeled tag.
DPP2 protein assumes a vital role in the degradation of specific oligopeptides, contributing to the cellular processes involved in peptide turnover. As an integral member of the dipeptidyl peptidase family, DPP2 is implicated in the hydrolysis of oligopeptide bonds, facilitating the breakdown of peptides into their constituent amino acids. This enzymatic activity underscores its significance in cellular catabolism and the regulation of peptide metabolism, illustrating its crucial role in maintaining the balance of intracellular peptide concentrations. The functional involvement of DPP2 in peptide degradation highlights its importance in cellular homeostasis and the dynamic processes governing peptide turnover within biological systems.
Measured by its ability to cleave the fluorogenic peptide substrate, Lys-Pro-AMC (KP-AMC). Read at excitation and emission wavelengths of 380 nm and 460 nm. The specific activity is 2025.169 pmol/min/µg, as measured under the described conditions.
Technical Parameters
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Species Human
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Source HEK293
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Tag C-His
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Accession
Q9UHL4 (G22-L492)
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Molecular Construction
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N-term
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DPP2 (G22-L492)
Accession # Q9UHL4 -
His
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C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
DPP7; DPP II; Dipeptidyl Peptidase 7; QPP; DPP2; Dipeptidyl Arylamidase II; Quiescent Cell Proline Dipeptidase; Dipeptidyl-Peptidase II; Dipeptidyl Aminopeptidase II; Dipeptidylpeptidase 7; Dipeptidyl Peptidase 2; Carboxytripeptidase; DPPII; DPP; Dipeptid
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AA Sequence
GARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL
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Molecular Weight
Approximately 60 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (238 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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