DPP7 - dipeptidyl peptidase 7 Gene

Homo sapiens

Also known as QPP; DPP2; DPPII

Gene ID: 29952 | Gene type: protein coding

About DPP7

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:137,110,546-137,118,306 (from NCBI)

This gene has 13 transcripts (splice variants), 191 orthologues and 2 paralogues. Ubiquitous expression in spleen (RPKM 29.2), testis (RPKM 27.1) and 25 other tissues.

Summary

The protein encoded by this gene is a post-proline cleaving Aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of Apoptosis, a state which is disrupted by inhibition of this novel serine protease. The Enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. [provided by RefSeq, Jul 2008]

DPP7 Products(1)

mRNA	Protein	Name
NM_013379.3	NP_037511.2	dipeptidyl peptidase 2 preproprotein

DPP7 Protein Structure

Peptidase_S28

0
100
200
300
400
492 a.a.

Protein Preferred Names

Protein Names

dipeptidyl peptidase 2

DPP II

Recombinant DPP7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75280	DPP2 Protein, Human (HEK293, His)	Q9UHL4 (G22-L492)	≥95%

Related Diseases

Diseases

Alias

Periodontitis, Chronic

Chronic Periodontitis

Periodontitis, Adult

Complement Component 7 Deficiency

C7 Deficiency

C7D

Facial Hemiatrophy

Parry-Romberg Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03967	DPP7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	DPP7	VGNC	VGNC:82328
Rattus norvegicus	DPP7	RGD	RGD:71073
Canis familiaris	DPP7	VGNC	VGNC:40076
Bos taurus	DPP7	VGNC	VGNC:28188
Mus musculus	DPP7	MGD	MGI:1933213
Macaca mulatta	DPP7	VGNC	VGNC:103257
Others	DPP7	NCBI