1. NF-κB
    Metabolic Enzyme/Protease
    Immunology/Inflammation
  2. NF-κB
    Reactive Oxygen Species
  3. Picroside II

Picroside II 

Cat. No.: HY-N0408
Handling Instructions

Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti-inflammatory and anti-apoptotic activities. picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways. Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury.

For research use only. We do not sell to patients.

Picroside II Chemical Structure

Picroside II Chemical Structure

CAS No. : 39012-20-9

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Description

Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti-inflammatory and anti-apoptotic activities. picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways[1]. Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury[2].

Molecular Weight

512.46

Formula

C₂₃H₂₈O₁₃

CAS No.

39012-20-9

SMILES

OC1=CC=C(C(OC(C2C3(CO)O2)C4C3C(OC5C(O)C(O)C(O)C(CO)O5)OC=C4)=O)C=C1OC

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Picroside II
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