1. GPCR/G Protein
    Metabolic Enzyme/Protease
  2. Angiotensin Receptor
    Neprilysin
  3. TD-0212

TD-0212 

Cat. No.: HY-114412
Handling Instructions

TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP.

For research use only. We do not sell to patients.

TD-0212 Chemical Structure

TD-0212 Chemical Structure

CAS No. : 1073549-10-6

Size Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP[1].

IC50 & Target

pKi: 8.9 (AT1)
pIC50: 9.2 (NEP)[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

527.65

Formula

C₂₈H₃₄FN₃O₄S

CAS No.

1073549-10-6

SMILES

OC(C1=CC=CC=C1C2=CC=C(CN3C(CNC([[email protected]](CC(C)C)S)=O)=C(CC)N=C3OCC)C(F)=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
TD-0212
Cat. No.:
HY-114412
Quantity:

TD-0212

Cat. No.: HY-114412