Doxorubicin-SMCC
Based on 1 publication(s) in Google Scholar
Doxorubicin-SMCC is a agent-linker conjugate for ADC. Doxorubicin-SMCC contains a non-cleavable ADC linker and a DNA topoisomerase II inhibitor Doxorubicin.
For research use only. We do not sell to patients.
- Purity: 98.37%
- CAS No.: 400647-59-8
- Formula: C39H42N2O14
- Molecular Weight:762.76
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Doxorubicin-SMCC
MoreAll Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
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Daunorubicins/Doxorubicins |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 400647-59-8
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Appearance Solid
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Molecular Weight 762.76
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Formula C39H42N2O14
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Color Orange to red
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SMILES
C[C@@H]1O[C@H](C[C@@H]([C@@H]1O)NC(C2CCC(CC2)CN3C(C=CC3=O)=O)=O)O[C@H]4C[C@](O)(C(CO)=O)CC5=C(O)C(C(C6=C7C(OC)=CC=C6)=O)=C(C7=O)C(O)=C45
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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ACS Omega
Preparation and Characterization of an Engineered FGF1 Conjugated to 161Tb for Targeting of FGFRs. [Abstract]2025 Feb 6;10(6):5730-5743. PMID: 39989790
Solvent & Solubility
DMSO : 125 mg/mL (163.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.3110 mL | 6.5551 mL | 13.1103 mL | 32.7757 mL |
| 5 mM | 0.2622 mL | 1.3110 mL | 2.6221 mL | 6.5551 mL | |
| 10 mM | 0.1311 mL | 0.6555 mL | 1.3110 mL | 3.2776 mL | |
| 15 mM | 0.0874 mL | 0.4370 mL | 0.8740 mL | 2.1850 mL | |
| 20 mM | 0.0656 mL | 0.3278 mL | 0.6555 mL | 1.6388 mL | |
| 25 mM | 0.0524 mL | 0.2622 mL | 0.5244 mL | 1.3110 mL | |
| 30 mM | 0.0437 mL | 0.2185 mL | 0.4370 mL | 1.0925 mL | |
| 40 mM | 0.0328 mL | 0.1639 mL | 0.3278 mL | 0.8194 mL | |
| 50 mM | 0.0262 mL | 0.1311 mL | 0.2622 mL | 0.6555 mL | |
| 60 mM | 0.0219 mL | 0.1093 mL | 0.2185 mL | 0.5463 mL | |
| 80 mM | 0.0164 mL | 0.0819 mL | 0.1639 mL | 0.4097 mL | |
| 100 mM | 0.0131 mL | 0.0656 mL | 0.1311 mL | 0.3278 mL |
Doxorubicin-SMCC Related Classifications
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