Isoarundinin II
Based on 1 Customer Validation
Isoarundinin II is a bibenzyl compound found in the pseudobulbs of Pleione grandiflora (Rolfe) Rolfe. Isoarundinin II scavenges DPPH free radicals.
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- Pureté : 94.41%
- CAS No.: 151538-56-6
- Formule: C22H22O4
- Masse moléculaire:350.41
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Stockage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Neutrophil | IC50 |
2.2 μM
Compound: 37
|
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
|
[PMID: 27525452] |
| Neutrophil | IC50 |
3.6 μM
Compound: 37
|
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
|
[PMID: 27525452] |
In Vitro
Isoarundinin II (0.2-0.6 g/L; 30 min) exhibits potent DPPH free radical scavenging activity, with an IC50 value ranging from 49.72 μM to 65.41 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 151538-56-6
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Appearance Solid
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Masse moléculaire 350.41
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Formule C22H22O4
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Color White to off-white
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SMILES
OC1=CC(OC)=CC(CCC2=CC=CC(O)=C2)=C1CC3=CC=C(O)C=C3
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Structure Classification
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Pureté et documentation
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Fiche technique (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)