Two new bibenzyls from Pleione grandiflora (Rolfe) Rolfe and their antioxidant activity

  • Nat Prod Res. 2023 Jul-Aug;37(15):2486-2492. doi: 10.1080/14786419.2022.2050909.
Wei Li  1 ,  Jia-Rui Fu  2 ,  Li-Jun Zheng  3 ,  Lin Ni  2 ,  Jun-Qing Liu  2 ,  Jun-Wen Zhai  1 ,  Zhuang Zhou  4 ,  Sha-Sha Wu  1
Affiliations
  • 1. College of Landscape Architecture, Fujian Agriculture and Forestry University, Fuzhou, P. R. China.
  • 2. Key Laboratory of Biopesticide and Chemical Biology, Ministry of Education, Fujian Agriculture and Forestry University, Fuzhou, P. R. China.
  • 3. Department of Pharmacy, Fujian Medical University Union Hospital, Fuzhou, P. R. China.
  • 4. Zhejiang Institute of Subtropical Crops, Zhejiang Academy of Agricultural Sciences, Wenzhou, P. R. China.
PMID: 35289695 DOI: 10.1080/14786419.2022.2050909
Abstract

Two new bibenzyls (1 and 2) were isolated from the pseudobulbs of Pleione grandiflora (Rolfe) Rolfe along with six known compounds, including isoarundinin I (3), isoarundinin II (4), bulbocodin D (5), batatasin III (6), 5,3'-dihydroxy- 4-(p-hydroxybenzyl)-3-methoxybibenzyl (7) and shancigusin F (8). Their structures were established on the basis of spectroscopic methods. These compounds showed potent DPPH free radical scavenging effects with IC50 values ranging from 49.72 ± 0.35 μM to 65.41 ± 0.49 μM.

Keywords
Orchidaceae; Pleione grandiflora (Rolfe) Rolfe; antioxidant; new bibenzyl compounds; pseudobulbs.
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