1. GPCR/G Protein
  2. Angiotensin Receptor
  3. Azilsartan mopivabil

Azilsartan mopivabil is the potent antagonist of angiotensin II receptor.

For research use only. We do not sell to patients.

Azilsartan mopivabil Chemical Structure

Azilsartan mopivabil Chemical Structure

CAS No. : 2271428-31-8

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Description

Azilsartan mopivabil is the potent antagonist of angiotensin II receptor[1].

IC50 & Target

angiotensin II receptor[1]

Molecular Weight

676.71

Formula

C38H36N4O8

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1ON=C(N1)C2=C(C=CC=C2)C3=CC=C(C=C3)CN4C(OCC)=NC5=C4C(C(OCC6=CC=C(OC(C(C)(C)C)=O)C(OC)=C6)=O)=CC=C5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 95 mg/mL (140.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4777 mL 7.3887 mL 14.7774 mL
5 mM 0.2955 mL 1.4777 mL 2.9555 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4777 mL 7.3887 mL 14.7774 mL 36.9434 mL
5 mM 0.2955 mL 1.4777 mL 2.9555 mL 7.3887 mL
10 mM 0.1478 mL 0.7389 mL 1.4777 mL 3.6943 mL
15 mM 0.0985 mL 0.4926 mL 0.9852 mL 2.4629 mL
20 mM 0.0739 mL 0.3694 mL 0.7389 mL 1.8472 mL
25 mM 0.0591 mL 0.2955 mL 0.5911 mL 1.4777 mL
30 mM 0.0493 mL 0.2463 mL 0.4926 mL 1.2314 mL
40 mM 0.0369 mL 0.1847 mL 0.3694 mL 0.9236 mL
50 mM 0.0296 mL 0.1478 mL 0.2955 mL 0.7389 mL
60 mM 0.0246 mL 0.1231 mL 0.2463 mL 0.6157 mL
80 mM 0.0185 mL 0.0924 mL 0.1847 mL 0.4618 mL
100 mM 0.0148 mL 0.0739 mL 0.1478 mL 0.3694 mL
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Azilsartan mopivabil Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Azilsartan mopivabil
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HY-145553
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