2. Natural Products
  3. Plants
  4. Celastraceae

Celastraceae

 

Celastraceae (53):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-32735
    Triptolide 38748-32-2 99.86%
    Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor.
    Triptolide
  • HY-13067
    Tripterin 34157-83-0 99.90%
    Tripterin (Celastrol) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM.
    Tripterin
  • HY-N0587
    Demethylzeylasteral 107316-88-1 99.90%
    Demethylzeylasteral is a triterpene compound isolated from Tripterygium wilfordii Hook F, with anti-inflammatory, immunosuppressive and anti-tumor activities. Demethylzeylasteral can significantly alleviates atherosclerosis (AS). Demethylzeylasteral inhibits triple-negative breast cancer invasion by blocking the canonical and non-canonical TGF-β signaling pathways.
    Demethylzeylasteral
  • HY-32736
    Triptonide 38647-11-9 99.73%
    Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC50 of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects.
    Triptonide
  • HY-N1937
    Pristimerin 1258-84-0 99.64%
    Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC50 of 93 nM.
    Pristimerin
  • HY-N6635
    trans-Nerolidol 40716-66-3
    trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity.
    trans-Nerolidol
  • HY-N10673
    10α-Hydroxyepigambogic acid 1164201-85-7
    10α-Hydroxyepigambogic acid can be extracted from Garcinia hanburyi. 10α-Hydroxyepigambogic acid can be used in the research of tumors.
    10α-Hydroxyepigambogic acid
  • HY-N10681
    Evonimine 41758-69-4
    Evonimine (Euonine) is an alkaloid isolated from Tripterygium wilfordii Hook. Evonimine exhibits significant inhibition of humoral-mediated immunity using the haemolytic response as an indicator, and shows good anti-feeding activity against the lepidopteran Spodoptera littoralis.
    Evonimine
  • HY-13674
    Maytansine 35846-53-8 99.50%
    Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations.
    Maytansine
  • HY-N0476
    Wilforlide A 84104-71-2 ≥98.0%
    Wilforlide A is a bioactive triterpene isolated from Tripterygium wilfordii Hook f. Wilforlide A has anti-inflammatory and immune suppressive effects.
    Wilforlide A
  • HY-N2922
    β-Amyrin 559-70-6 99.38%
    β-Amyrin, an ingredient of Celastrus hindsii, blocks amyloid β (Aβ)-induced long-term potentiation (LTP) impairment. β-amyrin is a promising candidate of treatment for AD.
    β-Amyrin
  • HY-N9437
    Betulin diacetate 1721-69-3
    Betulin diacetate, a triterpene and derivative of Betulin, is an anti-AID agent and also possesses anti-cancer activity.
    Betulin diacetate
  • HY-N0475
    Triptophenolide 74285-86-2 99.93%
    Triptophenolide is a colorless crystalline plate isolated from ethyl acetate extracts of Tripterygium wilfordii.
    Triptophenolide
  • HY-N4110
    Friedelin 559-74-0 ≥99.0%
    Friedelin is isolated from isolated from the leaves of Maytenus ilicifolia(Mart). Friedelin is a noncompetitive inhibitor of CYP3A4 with IC50 and Kivalues of 10.79  μM and 6.16  μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1 with IC50 and Ki values of 22.54  μM and 18.02 μM, respectively.
    Friedelin
  • HY-N0899
    Wilforine 11088-09-8 98.30%
    Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T.
    Wilforine
  • HY-N6596
    7-Hydroxy-4-chromone 59887-89-7 99.94%
    7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM.
    7-Hydroxy-4-chromone
  • HY-N1072
    Wilforgine 37239-47-7 99.67%
    Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system.
    Wilforgine
  • HY-N3511
    Triptonine B 168009-85-6 ≥98.0%
    Triptonine B, a sesquiterpene pyridine alkaloid, inhibits HIV replication in H9 lymphocytes with an EC50 value of <0.10 μg/mL.
    Triptonine B
  • HY-N1120
    Triptoquinone B 142937-50-6
    Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells.
    Triptoquinone B
  • HY-N3507
    Euojaponine D 128397-42-2
    Euojaponine D is a sesquiterpene alkaloids from Euonymus japonica (Celastraceae). Celastraceae has potent insecticidal activity.
    Euojaponine D