2. Natural Products
  3. Plants
  4. Celastraceae
  5. Tripterygium wilfordii Hook. f.

Tripterygium wilfordii Hook. f.

Tripterygium wilfordii Hook. f. (77):

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-32735
    Triptolide 38748-32-2 99.94%
    Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor.
    Triptolide
  • HY-13067
    Celastrol 34157-83-0 99.90%
    Celastrol (Tripterine;Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. In addition, Celastrol is also an antibiotic with potent antimicrobial activity against standard and clinical methicillin-resistant Staphylococcus aureus (MRSA) strains, inducing oxidative stress and inhibiting DNA synthesis by binding to P5CDH.
    Celastrol
  • HY-N0587
    Demethylzeylasteral 107316-88-1 99.92%
    Demethylzeylasteral is an orally active triterpenoid compound isolated from Tripterygium wilfordii, which has functions such as anti-inflammatory, anti-tumor, anti fertility, estrogen metabolism regulation, immune suppression, and immune system regulation [1][2].
    Demethylzeylasteral
  • HY-32736
    Triptonide 38647-11-9 99.89%
    Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC50 of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects.
    Triptonide
  • HY-N1937
    Pristimerin 1258-84-0 99.81%
    Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC50 of 93 nM.
    Pristimerin
  • HY-N17352
    (20α)-29-Hydroxy-3-oxo-olean-12-en-28-oic acid 273198-93-9
    (20α)-29-Hydroxy-3-oxo-olean-12-en-28-oic acid (Compound 4) is a triterpenoid. (20α)-29-Hydroxy-3-oxo-olean-12-en-28-oic acid can be isolated from T. wilfordii.
    (20α)-29-Hydroxy-3-oxo-olean-12-en-28-oic acid
  • HY-N17528
    Triptohypol E 268541-25-9
    Triptohypol E is a triterpenoid compound and nitric oxide production inhibitor that can be isolated from the leaves of Rhododendron dauricum L. Triptohypol E inhibits nitric oxide production in LPS-stimulated macrophages in a dose-dependent manner.
    Triptohypol E
  • HY-N18354
    Tripterygiumine H 73257-63-3
    Tripterygiumine H (Compound 8) is an alkaloid found in the dried roots of Tripterygium wilfordii.
    Tripterygiumine H
  • HY-N0476
    Wilforlide A 84104-71-2 98.0%
    Wilforlide A is a bioactive triterpene isolated from Tripterygium wilfordii Hook f. Wilforlide A has anti-inflammatory and immune suppressive effects.
    Wilforlide A
  • HY-117469
    Triptohypol C 193957-88-9
    Triptohypol C, a Tripterin (HY-13067) derivative, is a potent Nur77-targeting anti-inflammatory agent with an Kd value of 0.87 μM. Triptohypol C inhibits inflammatory response by promoting the interactions of Nur77 with TRAF2 and p62/SQSTM1.
    Triptohypol C
  • HY-13067R
    Celastrol (Standard) 34157-83-0
    Celastrol (Standard) is the analytical standard of Celastrol. This product is intended for research and analytical applications. Celastrol (Tripterine;Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM.
    Celastrol (Standard)
  • HY-N0475
    Triptophenolide 74285-86-2 99.98%
    Triptophenolide (Hypolide) is a colorless crystal isolated from the ethyl acetate extract of Tripterygium wilfordii. Triptophenolide is an orally active pan‑antagonist of the androgen receptor (AR) with an IC50 of 467 nM against human wild‑type AR. Triptophenolide reduces AR expression, inhibits AR nuclear translocation, downregulates prostate‑specific antigen mRNA levels, and suppresses the growth of AR‑positive prostate cancer cells. Triptophenolide shows anti-tumor effects against breast cancer by inhibiting cell proliferation and migration, inducing G1-phase arrest and apoptosis, repressing xenograft tumor growth. Triptophenolide inhibits pyroptosis, alleviates tissue inflammation, and ameliorates synovial injury. Triptophenolide can be used for the study of prostate cancer, rheumatoid arthritis and breast cancer.
    Triptophenolide
  • HY-N6596
    7-Hydroxy-4H-chromen-4-one 59887-89-7 99.85%
    7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM.
    7-Hydroxy-4H-chromen-4-one
  • HY-N0899
    Wilforine 11088-09-8 99.47%
    Wilforine is an orally active JAK-STAT pathway inhibitor with immunomodulatory effects and the ability to inhibit osteoclast fusion. Wilforine disrupts lipid raft integrity, reprograms cholesterol and glycosphingolipid metabolic pathways, regulates NF-κB and the complement system, and modulates the expression of various interleukins. Wilforine also inhibits the Wnt11/β-catenin signaling pathway and suppresses the proliferation of fibroblast-like synoviocytes. Wilforine can serve as a quality and pharmacokinetic marker for Tripterygium glycoside tablets, and can be applied to research on related diseases such as rheumatoid arthritis, inflammatory osteolysis, and SAPHO syndrome.
    Wilforine
  • HY-N10406
    Triptonoterpene 99694-87-8 98.47%
    Triptonoterpene is a natural product that can be isolated from the roots of Tripterygium wilfordii Hook. f..
    Triptonoterpene
  • HY-N1072
    Wilforgine 37239-47-7 99.67%
    Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system.
    Wilforgine
  • HY-32735R
    Triptolide (Standard) 38748-32-2
    Triptolide (Standard) is the analytical standard of Triptolide. This product is intended for research and analytical applications. Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor.
    Triptolide (Standard)
  • HY-N0587R
    Demethylzeylasteral (Standard) 107316-88-1
    Demethylzeylasteral (Standard) is the analytical standard of Demethylzeylasteral. This product is intended for research and analytical applications. Demethylzeylasteral is an orally active triterpenoid compound isolated from Tripterygium wilfordii, which has functions such as anti-inflammatory, anti-tumor, anti fertility, estrogen metabolism regulation, immune suppression, and immune system regulation .
    Demethylzeylasteral (Standard)
  • HY-N1121
    Triptonodiol 117456-87-8 98.0%
    Triptonodiol can be isolated from Trypterygium wilfordii. Triptonodiol has anti-inflammatory and anti-cancer activity. Triptonodiol inhibits the biological activity of GSK.
    Triptonodiol
  • HY-N8879
    Wilforol A 167882-66-8 98.64%
    Wilforol A ((-)-Wilforol A), plant metabolite, is a pentacyclic triterpenoid. Wilforol A can be used for the research of various biochemical studies.
    Wilforol A