1. Natural Products
  2. Plants
  3. Celastraceae


Celastraceae (57):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-32735
    Triptolide 38748-32-2 99.86%
    Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor.
  • HY-13067
    Celastrol 34157-83-0 99.90%
    Celastrol (Tripterine;Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM.
  • HY-N0587
    Demethylzeylasteral 107316-88-1 99.45%
    Demethylzeylasteral is a triterpene compound isolated from Tripterygium wilfordii Hook F, with anti-inflammatory, immunosuppressive and anti-tumor activities. Demethylzeylasteral can significantly alleviates atherosclerosis (AS). Demethylzeylasteral inhibits triple-negative breast cancer invasion by blocking the canonical and non-canonical TGF-β signaling pathways.
  • HY-32736
    Triptonide 38647-11-9 99.87%
    Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC50 of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects.
  • HY-13674
    Maytansine 35846-53-8 99.50%
    Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations.
  • HY-N1121
    Triptonodiol 117456-87-8
    Triptonodiol can be isolated from Trypterygium wilfordii. Triptonodiol has anti-inflammatory and anti-cancer activity. Triptonodiol inhibits the biological activity of GSK.
  • HY-N8444
    Triptoquinone A 142950-86-5
    Triptoquinone A, an interleukin 1 inhibitor, inhibits endomycin (LPS) or interleukin (IL-1β)-promoted induction of nitric oxide synthase (NOS) in vascular smooth muscle, thereby inhibiting Arg-induced vascular relaxation.
    Triptoquinone A
  • HY-N11573
    Kaempferol 3,7-bis(α-L-rhamnose-D-glucose) 1392495-12-3
    Kaempferol 3,7-bis(α-L-rhamnose-D-glucose) (compound 1) is a flavonoid glycoside that can be found in Euonymus fortune.
    Kaempferol 3,7-bis(α-L-rhamnose-D-glucose)
  • HY-N1937
    Pristimerin 1258-84-0 99.64%
    Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC50 of 93 nM.
  • HY-N2922
    β-Amyrin 559-70-6 99.38%
    β-Amyrin, an ingredient of Celastrus hindsii, blocks amyloid β (Aβ)-induced long-term potentiation (LTP) impairment. β-amyrin is a promising candidate of treatment for AD.
  • HY-N0476
    Wilforlide A 84104-71-2 ≥98.0%
    Wilforlide A is a bioactive triterpene isolated from Tripterygium wilfordii Hook f. Wilforlide A has anti-inflammatory and immune suppressive effects.
    Wilforlide A
  • HY-117469
    Triptohypol C 193957-88-9
    Triptohypol C, a Tripterin (HY-13067) derivative, is a potent Nur77-targeting anti-inflammatory agent with an Kd value of 0.87 μM. Triptohypol C inhibits inflammatory response by promoting the interactions of Nur77 with TRAF2 and p62/SQSTM1.
    Triptohypol C
  • HY-N0475
    Triptophenolide 74285-86-2 99.93%
    Triptophenolide is a colorless crystalline plate isolated from ethyl acetate extracts of Tripterygium wilfordii.
  • HY-N6635
    trans-Nerolidol 40716-66-3
    trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity.
  • HY-N4110
    Friedelin 559-74-0 ≥99.0%
    Friedelin is isolated from isolated from the leaves of Maytenus ilicifolia(Mart). Friedelin is a noncompetitive inhibitor of CYP3A4 with IC50 and Kivalues of 10.79  μM and 6.16  μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1 with IC50 and Ki values of 22.54  μM and 18.02 μM, respectively.
  • HY-N9437
    Betulin diacetate 1721-69-3
    Betulin diacetate, a triterpene and derivative of Betulin, is an anti-AID agent and also possesses anti-cancer activity.
    Betulin diacetate
  • HY-N3506
    Wilfortrine 37239-48-8 98.83%
    Wilfortrine is a bioactive sesquiterpene alkaloid. Wilfortrine exhibits immunosuppresive effects. Wilfortrine also can inhibit leukaemia cell growth in mice and shows anti-HIV activity.
  • HY-N3511
    Triptonine B 168009-85-6 ≥98.0%
    Triptonine B, a sesquiterpene pyridine alkaloid, inhibits HIV replication in H9 lymphocytes with an EC50 value of <0.10 μg/mL.
    Triptonine B
  • HY-N6596
    7-Hydroxy-4-chromone 59887-89-7 99.94%
    7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM.
  • HY-N6912
    Regelidine 114542-54-0 98.08%
    Regelidine is a natural product isolated from the stems of Tripterygium regelii.