2. Cell Cycle/DNA Damage Apoptosis
  3. Topoisomerase Apoptosis
  4. Topoisomerase II inhibitor 14

Topoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO.

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Topoisomerase II inhibitor 14 Chemical Structure

Topoisomerase II inhibitor 14 Chemical Structure

CAS No. : 305343-00-4

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Topoisomerase II inhibitor 14 Related Antibodies

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Description

Topoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO[1].

In Vivo

Topoisomerase II inhibitor 14 (compound 2f)

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

332.19

Formula

C15H11Cl2N5
CAS No.
SMILES

NC1=NC(C2=CC=C(Cl)C=C2Cl)N3C4=CC=CC=C4N=C3N1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Topoisomerase II inhibitor 14 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerase II inhibitor 14305343-00-4Topoisomerase II inhibitor14Topoisomerase II inhibitor-14TopoisomeraseApoptosisCytotoxicityHNSCCTopoisomerase IITricyclic imidazotriazinesInhibitorinhibitorinhibit

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