1. Anti-infection
  2. Parasite
  3. Plm IV inhibitor-2

Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites.

For research use only. We do not sell to patients.

Plm IV inhibitor-2 Chemical Structure

Plm IV inhibitor-2 Chemical Structure

CAS No. : 1539276-38-4

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Description

Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites[1].

IC50 & Target[1]

Plm IV

24 nM (IC50)

Plm II

70 nM (IC50)

Plm I

0.3 μM (IC50)

Molecular Weight

642.87

Formula

C39H54N4O4

CAS No.
SMILES

CCCN(CCC)C(C1=CC(C(N[C@H]([C@H](O)CNC(C)(C2=CC(OC)=CC=C2)C)CC3=CC=CC=C3)=O)=CC(N4CCCCC4)=C1)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Plm IV inhibitor-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Plm IV inhibitor-2
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HY-148035
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