1. Cell Cycle/DNA Damage
  2. p97
  3. MSC1094308

MSC1094308 

Cat. No.: HY-123872
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MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase (VCP)/p97 and the type I AAA ATPase VPS4B, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively.

For research use only. We do not sell to patients.

MSC1094308 Chemical Structure

MSC1094308 Chemical Structure

CAS No. : 2219320-08-6

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Description

MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase (VCP)/p97 and the type I AAA ATPase VPS4B, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively[1].

IC50 & Target

IC50: 0.71 μM (VPS4B), 7.2 μM (p97)[1].

Molecular Weight

462.55

Formula

C₂₉H₂₉F₃N₂

CAS No.

2219320-08-6

SMILES

FC1=CC=C(C(C2=CC=C(F)C=C2)CCCNCC3CCC(NC4=C5C=C(F)C=C4)=C5C3)C=C1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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MSC1094308
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