1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Cadherins
  5. Desmocollin-2
  6. DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc)

DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc)

Cat. No.: HY-P76302
Handling Instructions

DSC2 (or Desmocollin-2) is an important component of desmosome connections between cells and plays a key role in the complex interaction network between plaque proteins and intermediate filaments. At these junctions, DSC2 contributes to cell-cell adhesion, promoting tissue cohesion and stability. DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc) is the recombinant rat-derived DSC2/Desmocollin-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc) is 666 a.a., with molecular weight of ~101.6 KDa.

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Description

DSC2 (or Desmocollin-2) is an important component of desmosome connections between cells and plays a key role in the complex interaction network between plaque proteins and intermediate filaments. At these junctions, DSC2 contributes to cell-cell adhesion, promoting tissue cohesion and stability. DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc) is the recombinant rat-derived DSC2/Desmocollin-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc) is 666 a.a., with molecular weight of ~101.6 KDa.

Background

Desmocollin-2 (DSC2) is a crucial component of intercellular desmosome junctions, playing a pivotal role in cell-cell adhesion. As part of desmosomes, DSC2 contributes to the intricate network that mediates cell-cell interactions. These junctions are essential for the maintenance of tissue integrity and provide structural support through the interaction of plaque proteins and intermediate filaments. DSC2's involvement in this molecular complex underscores its significance in ensuring the cohesion and stability of tissues, particularly those subjected to mechanical stress. The protein's function in promoting cell-cell adhesion highlights its importance in the maintenance of tissue architecture and overall cellular integrity. (

Species

Rat

Source

HEK293

Tag

C-hFc

Accession

Q3T1K6 (C29-P694)

Gene ID

291760  [NCBI]

Molecular Construction
N-term
DSC2 (C29-P694)
Accession # Q3T1K6
hFc
C-term
Synonyms
Cadherin family member 2; CDHF2; DSC3; Desmosomal glycoprotein II
Molecular Weight

Approximately 101.6 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc)
Cat. No.:
HY-P76302
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