2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. AAA-pNA

AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

AAA-pNA

AAA-pNA Chemical Structure

CAS No. : 60354-61-2

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Based on 1 publication(s) in Google Scholar

AAA-pNA Related Antibodies

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Description

AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity[1].

Molecular Weight

351.36

Formula

C15H21N5O5
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ala-Ala-{Ala-pNA}
Sequence Shortening

AA-{Ala-pNA}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (284.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8461 mL 14.2304 mL 28.4608 mL
5 mM 0.5692 mL 2.8461 mL 5.6922 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8461 mL 14.2304 mL 28.4608 mL 71.1521 mL
5 mM 0.5692 mL 2.8461 mL 5.6922 mL 14.2304 mL
10 mM 0.2846 mL 1.4230 mL 2.8461 mL 7.1152 mL
15 mM 0.1897 mL 0.9487 mL 1.8974 mL 4.7435 mL
20 mM 0.1423 mL 0.7115 mL 1.4230 mL 3.5576 mL
25 mM 0.1138 mL 0.5692 mL 1.1384 mL 2.8461 mL
30 mM 0.0949 mL 0.4743 mL 0.9487 mL 2.3717 mL
40 mM 0.0712 mL 0.3558 mL 0.7115 mL 1.7788 mL
50 mM 0.0569 mL 0.2846 mL 0.5692 mL 1.4230 mL
60 mM 0.0474 mL 0.2372 mL 0.4743 mL 1.1859 mL
80 mM 0.0356 mL 0.1779 mL 0.3558 mL 0.8894 mL
100 mM 0.0285 mL 0.1423 mL 0.2846 mL 0.7115 mL
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AAA-pNA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AAA-pNA60354-61-2Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteaseschromogenic substrateTripeptidyl-peptidase IIInhibitorinhibitorinhibit

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