Halazone

Cat. No.: HY-B1386 Purity: ≥75.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a K_d value of 1.45 µM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water.

For research use only. We do not sell to patients.

Halazone Chemical Structure

CAS No. : 80-13-7

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Free Sample (0.1 - 0.5 mg)		Apply Now
50 mg	USD 35	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 48	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
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Description

In Vitro

Halazone is chemically closely related to Chloramine-T, the nitrogen atom is linked with two instead of one chlorine atom and, certainly more important here, a methyl group is replaced by a carboxyl group. The effect of Halazone on the sodium current is studied in voltage-clamped single nerve fibers of the frog. The oxidant Halazone drastically inhibits inactivation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

270.09

Formula

C₇H₅Cl₂NO₄S

CAS No.

80-13-7

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC=C(S(=O)(N(Cl)Cl)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (370.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7025 mL	18.5123 mL	37.0247 mL
5 mM	0.7405 mL	3.7025 mL	7.4049 mL
10 mM	0.3702 mL	1.8512 mL	3.7025 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥75.0%

Select Batch:

Data Sheet (244 KB) SDS (251 KB)

COA (249 KB) HNMR (260 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7025 mL	18.5123 mL	37.0247 mL	92.5617 mL
	5 mM	0.7405 mL	3.7025 mL	7.4049 mL	18.5123 mL
	10 mM	0.3702 mL	1.8512 mL	3.7025 mL	9.2562 mL
	15 mM	0.2468 mL	1.2342 mL	2.4683 mL	6.1708 mL
	20 mM	0.1851 mL	0.9256 mL	1.8512 mL	4.6281 mL
	25 mM	0.1481 mL	0.7405 mL	1.4810 mL	3.7025 mL
	30 mM	0.1234 mL	0.6171 mL	1.2342 mL	3.0854 mL
	40 mM	0.0926 mL	0.4628 mL	0.9256 mL	2.3140 mL
	50 mM	0.0740 mL	0.3702 mL	0.7405 mL	1.8512 mL
	60 mM	0.0617 mL	0.3085 mL	0.6171 mL	1.5427 mL
	80 mM	0.0463 mL	0.2314 mL	0.4628 mL	1.1570 mL
	100 mM	0.0370 mL	0.1851 mL	0.3702 mL	0.9256 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Halazone80-13-7Inhibitorinhibitorinhibit

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