80-13-7
Chemical Structure
Halazone
- CAS No.: 80-13-7
- Formula:C7H5Cl2NO4S
- Molecular Weight:270.09
IUPAC Name: 4-(N,N-dichlorosulfamoyl)benzoic acid
InChIKey: XPDVQPODLRGWPL-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(S(=O)(N(Cl)Cl)=O)C=C1
Biological Activity: Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 μM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Halazone | 75.0% | Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 μM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water. | ||||||||||||||||||||
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Dichloramine-T (Standard) | ≥98% | Dichloramine-T (Standard) is the analytical standard of Dichloramine-T (HY-105840). This product is intended for research and analytical applications. Dichloramine-T is a strong oxidizer and disinfectant, with strong oxidation and sterilization. Dichloramine-T is also widely used in the medical and health field for disinfection and sterilization operations. | ||||||||||||||||||||
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4'-(Methylsulfonyl)acetophenone | 99.43% | p-Methylsulfonylacetophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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4-Chlorobenzoic acid (Standard) | 99.07% | 4-Chlorobenzoic acid (Standard) is the analytical standard of 4-Chlorobenzoic acid (HY-41465). This product is intended for research and analytical applications. 4-Chlorobenzoic acid is a halogenated aromatic compound that can be used as an industrial chemical and an intermediate in drug synthesis. 4-Chlorobenzoic acid is a persistent organic micropollutant and can be biodegraded through a direct dehalogenation pathway. | ||||||||||||||||||||
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Chloramine-T | 98.0% | Chloramine-T is a titrimetric reagent, and an oxidizing agent. Chloramine-T is an oxidizing biocide. | ||||||||||||||||||||
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Carzenide | 99.45% | Carzenide (4-Sulfamoylbenzoic acid) is the major circulating metabolite of Mafenide (HY-B0614) in plasma. Carzenide is a strong CAII competitive inhibitor. Carzenide can be used in the research of epilepsy and cervical cancer. | ||||||||||||||||||||
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5-Sulfosalicylic acid (Standard) | ≥98% | 5-Sulfosalicylic acid (Standard) is the analytical standard of 5-Sulfosalicylic acid. This product is intended for research and analytical applications. 5-Sulfosalicylic acid is a sulfonated salicylic acid derivative. 5-Sulfosalicylic acid is effective against the breast cancer cell lines, with less toxicity. 5-Sulfosalicylic acid has antioxidant activities. | ||||||||||||||||||||
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Terephthalic acid-13C2 | 99.60% | Terephthalic acid-13C2 is the 13C-labeled Terephthalic acid. Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models. | ||||||||||||||||||||
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4-Chloro-3-sulfamoylbenzoic acid | 99.94% | 4-Chloro-3-sulfamoylbenzoic acid is a weak inhibitor of human carbonic anhydrase isoforms hCA I, hCA II, hCA IV, and hCA IX, and a synthesis intermediate for carbonic anhydrase inhibitors. 4-Chloro-3-sulfamoylbenzoic acid is the major metabolite of tripamide detected in tissues, urine, and feces of rats and rabbits following Tripamide (HY-106570) administration. 4-Chloro-3-sulfamoylbenzoic acid can be used for the study of carbonic anhydrase inhibition and species differences in drug metabolism. | ||||||||||||||||||||
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4-Formylbenzoic acid | 99.36% | 4-Formylbenzoic acid is an intermediate in the synthesis of terepthalic acid. 4-Formylbenzoic acid can react with barium carbonate to yield two-dimensional barium(II) coordination polymer. 4-Formylbenzoic acid can also be used in the synthesis of acid functionalized mesoporous silica catalyst via the condensation. | ||||||||||||||||||||
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N-p-Tosylglycine | 98.21% | N-p-Tosylglycine is a Glycine (HY-Y0966) derivative. | ||||||||||||||||||||
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References
- [1]. M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64. [Content Brief]
- [2]. Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91. [Content Brief]