80-13-7
80-13-7
Chemical Structure
Halazone
- CAS No.: 80-13-7
- Formula:C7H5Cl2NO4S
- Molecular Weight:270.09
IUPAC Name: 4-(N,N-dichlorosulfamoyl)benzoic acid
InChIKey: XPDVQPODLRGWPL-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(S(=O)(N(Cl)Cl)=O)C=C1
Biological Activity: Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 μM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water[1][2].
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Halazone | 75.0% | Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 μM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water. | ||||||||||||||||||||
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References
- [1]. M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64. [Content Brief]
- [2]. Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91. [Content Brief]
