Phosphatase-IN-1
Based on 1 Customer Validation
Phosphatase-IN-1 (compound II-8), a propranolol (HY-B0573B) derivative, is a phosphatidate phosphatase (Pah) inhibitor. Phosphatase-IN-1 can binds to MoPah1, with an affinity constant of 19.8 μM. Phosphatase-IN-1 inhibits growth of plant pathogens and shows anti-fungal ability. Phosphatase-IN-1 is not toxic to rice seedlings and wheat heads.
For research use only. We do not sell to patients.
- Purity: 99.88%
- CAS No.: 2889356-55-0
- Formula: C16H16Cl2FNO2
- Molecular Weight:344.21
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Phosphatase-IN-1 (compound II-8) effectively inhibits vegetative growth of eight plant pathogens at 223 60 µM[1].
Phosphatase-IN-1 shows attenuated inhibition on the Mopah1 mutant in comparison to the WT strain[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2889356-55-0
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Appearance Solid
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Molecular Weight 344.21
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Formula C16H16Cl2FNO2
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Color White to light yellow
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SMILES
FC1=CC=C(CNCC(COC2=CC=C(C=C2Cl)Cl)O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 35 mg/mL (101.68 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9052 mL | 14.5260 mL | 29.0520 mL | 72.6301 mL |
| 5 mM | 0.5810 mL | 2.9052 mL | 5.8104 mL | 14.5260 mL | |
| 10 mM | 0.2905 mL | 1.4526 mL | 2.9052 mL | 7.2630 mL | |
| 15 mM | 0.1937 mL | 0.9684 mL | 1.9368 mL | 4.8420 mL | |
| 20 mM | 0.1453 mL | 0.7263 mL | 1.4526 mL | 3.6315 mL | |
| 25 mM | 0.1162 mL | 0.5810 mL | 1.1621 mL | 2.9052 mL | |
| 30 mM | 0.0968 mL | 0.4842 mL | 0.9684 mL | 2.4210 mL | |
| 40 mM | 0.0726 mL | 0.3632 mL | 0.7263 mL | 1.8158 mL | |
| 50 mM | 0.0581 mL | 0.2905 mL | 0.5810 mL | 1.4526 mL | |
| 60 mM | 0.0484 mL | 0.2421 mL | 0.4842 mL | 1.2105 mL | |
| 80 mM | 0.0363 mL | 0.1816 mL | 0.3632 mL | 0.9079 mL | |
| 100 mM | 0.0291 mL | 0.1453 mL | 0.2905 mL | 0.7263 mL |