Topoisomerase II inhibitor 10
Topoisomerase II inhibitor 10 (compound 32a) is a potent topoisomerase II inhibitor with an IC50 value of 7.45 μM. Topoisomerase II inhibitor 10 causes cell cycle arrest at G2-M phase and induces apoptosis of HepG-2 cells. Topoisomerase II inhibitor 10 has excellent anti-proliferative activities against HepG-2, MCF-7, and HCT-116 cells.
For research use only. We do not sell to patients.
- CAS No.: 2488208-96-2
- Formula: C27H20N6O7S
- Molecular Weight:572.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Topoisomerase Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
Topoisomerase II 7.45 μM (IC50) |
Chemical Information
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CAS No. 2488208-96-2
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Molecular Weight 572.55
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Formula C27H20N6O7S
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SMILES
O=C(O)C1=CC=C(NC(CSC2=NN=C3N2N(CC(NC4=CC=C(C(O)=O)C=C4)=O)C(C5=C3C=CC=C5)=O)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Topoisomerase II inhibitor 10 Related Classifications
HY-147839 Related Classifications
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