hCAII-IN-4
hCAII-IN-4 (Compound 12j) is a potent hCA II inhibitor with an IC50 of 7.78 μM. hCAII-IN-4 also inhibits β-glucuronidase with an IC50 of 773.9 μM.
For research use only. We do not sell to patients.
- CAS No.: 2816080-18-7
- Formula: C31H23NO9
- Molecular Weight:553.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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hCA II 7.78 μM (IC50) |
β-glucuronidase 773.9 μM (IC50) |
The high-rank inhibitory potential of hCAII-IN-4 (Compound 12j) is attributed to the presence of the electron-donating OH group at C-7 of the coumarin motif[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2816080-18-7
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Molecular Weight 553.52
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Formula C31H23NO9
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SMILES
O=C(C(C1C2=CC=CC=C2OCC(C3=O)=CC4=C(O3)C=CC=C4)=C(N)OC(C5=C(O6)C=C(O)C=C5)=C1C6=O)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)