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KN-93 hydrochloride

97 Cited Publications
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Based on 97 publication(s) in Google Scholar

KN-93 hydrochloride is a cell-permeable, reversible and competitive inhibitor calmodulin-dependent kinase type II (CaMKII) with a Ki of 370 nM.

For research use only. We do not sell to patients.

  • Purity: 99.64%
  • CAS No.: 1956426-56-4
  • Formula: C26H30Cl2N2O4S
  • Molecular Weight:537.50
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • KN-93 hydrochloride Chemical Structure
    KN-93 hydrochloride Chemical Structure
  • Experimental Validation Results for KN-93 hydrochloride
  • Experimental Validation Results for KN-93 hydrochloride
  • Experimental Validation Results for KN-93 hydrochloride
  • Experimental Validation Results for KN-93 hydrochloride
CAS No.: 1956426-56-4
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • KN-93 hydrochloride Chemical Structure
    KN-93 hydrochloride Chemical Structure
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  • 1/16

    KN-93 hydrochloride purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2020 Feb;41(2):218-228. [Abstract]

    Customer Validation
     HUVECs are pretreated with KN93 for 1 h, followed by ZYZ-803 (1 μM) for 30 min. Protein levels are assessed by Western blot.

  • 1/16

    KN-93 hydrochloride purchased from MedChemExpress. Usage Cited in: Diabetes. 2018 Sep;67(9):1748-1760. [Abstract]

    Customer Validation
     Immunoblotting analysis of PCK1, G6Pase, and phospho-CaMKIIγ proteins in NTG and HCTG hepatocytes in response to PGF2α and in the presence or absence of KN-93 treatment.

  • 1/16

    KN-93 hydrochloride purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2018 Apr 12:9:362. [Abstract]

    Customer Validation
     MK 733-increased biotinylated α7nAChR protein is blocked by the addition of KN93 (P<0.01, n=6 mice).

  • 1/16

    KN-93 hydrochloride purchased from MedChemExpress. Usage Cited in: Exp Cell Res. 2018 Mar 15;364(2):198-207. [Abstract]

    Customer Validation
     Western blot analysis of β-catenin protein level in HEK 293T cells stimulated for 12h with rAGR2 (100 ng/mL) coupled with or without KN93 (10 μM).

  • KN-93 hydrochloride