GNRHR2 Protein, Rhesus Macaque (Cell-Free, His)
Based on 1 Customer Validation
The GNRHR2 Protein serves as a receptor for gonadotropin-releasing hormone II (GnRH II), initiating its action through association with G proteins that activate a phosphatidylinositol-calcium second messenger system. GNRHR2 Protein, Rhesus Macaque (Cell-Free, His) is the recombinant Rhesus Macaque-derived GNRHR2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.
- Species: Rhesus Macaque
- Source: E. coli Cell-free
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The GNRHR2 Protein serves as a receptor for gonadotropin-releasing hormone II (GnRH II), initiating its action through association with G proteins that activate a phosphatidylinositol-calcium second messenger system. GNRHR2 Protein, Rhesus Macaque (Cell-Free, His) is the recombinant Rhesus Macaque-derived GNRHR2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.
Background
GNRHR2, the receptor for gonadotropin-releasing hormone II (GnRH II), plays a pivotal role in cellular signaling by associating with G proteins to activate a phosphatidylinositol-calcium second messenger system. This molecular interaction enables GNRHR2 to transduce signals triggered by GnRH II, thereby regulating downstream cellular responses. The intricate coupling between GNRHR2 and intracellular signaling cascades underscores its significance in mediating the physiological effects of GnRH II and highlights its role as a key player in reproductive processes and hormonal regulation.
Technical Parameters
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Species Rhesus Macaque
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Source E. coli Cell-free
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Tag N-6*His
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Accession
Q95JG1 (M1-I379)
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Gene ID574163
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Molecular Construction
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N-term
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10*His
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GNRHR2 (M1-I379)
Accession # Q95JG1 -
C-term
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Protein Length
Full Length
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Synonyms
GNRHR2; Putative Gonadotropin-Releasing Hormone II Receptor; Gonadotropin Releasing Hormone Receptor 2 (Pseudogene); Gonadotropin-Releasing Hormone (Type 2) Receptor 2; GNRHR2P; Type II Gonadotropin-Releasing Hormone Receptor; Type II GnRH Receptor; GnRH
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AA Sequence
MSAGNGTPWGSAAGEESWAASGVAVEGSELPTFSAAAKVRVGVTIVLFVSSAGGNLAVLWSVTRPQPSQLRPSPVRTLFAHLAAADLLVTFVVMPLDATWNITVQWLAEDIACRTLMFLKLMAMYSAAFLPVVIGLDRQAAVLNPLGSRSGVRKLLGAAWGLSFLLALPQLFLFHTVHRAGPVPFTQCVTKGSFKARWQETTYNLFTFRCLFLLPLTAMAICYSHIVLSVSSPQTRKGSHAPAGEFALCRSFDNCPRVRLWALRLALLILLTFILCWTPYYLLGLWYWFSPTMLTEVPPSLSHILFLFGLLNAPLDPLLYGAFTLGCQRGHQELSIDSSNEGSGRMLQQEIHALRQQEVQKTVTSRSAGETKDISITSI
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Predicted Molecular Mass
42.4 kDa
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Molecular Weight
Approximately 40 kDa (Monomer) & 80 kDa (Dimer), based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, 0.05% Brij-78, 6%trehalose, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (237 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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