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Synapsin 2 Antibody (YA1898)

(Synonyms: SYN 2; SYN II; SYN IIa; SYN IIb; SYN2; Synapsin2; SynapsinII; SYNII; SYNIIa; SYNIIb)
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Synapsin 2 Antibody (YA1898) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Synapsin 2.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

  • Conjugation:
    Non-conjugated
  • Synapsin 2 Antibody (YA1898) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:1000-1:2000 1:50-1:100

Product Details

Description

Synapsin 2 Antibody (YA1898) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Synapsin 2.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 75 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 63 kDa
Species Reactivity Database
Immunogen

A synthesized peptide derived from human Synapsin II aa500-582/582.

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Synapsin 2 is a Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons

  • Subcellular Localization

    Synapse

  • Expression


    Tissue_specificity:Central and peripheral nervous systems

  • Isoforms & Post-Translational Modification

    Q92777 has 2 isomers: Q92777-1: 62996 Da (predicted); Q92777-2: 52311 Da (predicted).
    Phosphorylation at Ser-10 dissociates synapsins from synaptic vesicles. Phosphorylation at Ser-425 by MAPK1/ERK2 and/or MAPK3/ERK1 may play a role in noradrenaline secretion by sympathetic neurons (By similarity)

  • Subunit

    Can form oligomers with SYN1 (PubMed:23406870). Interacts with CAPON

  • SwissProt ID

    Q92777

  • Gene ID
    6854 [NCBI]
  • Synonyms

    SYN 2; SYN II; SYN IIa; SYN IIb; SYN2; Synapsin2; SynapsinII; SYNII; SYNIIa; SYNIIb

  • Research Field

    Signal Transduction

Synapsin 2 Antibody (YA1898) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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