1. GPCR/G Protein
  2. Angiotensin Receptor
  3. Angiotensin II (3-8), human TFA

Angiotensin II (3-8), human TFA 

Cat. No.: HY-P1515A Purity: 98.99%
Handling Instructions

Angiotensin II (3-8), human (TFA) is a less effective agonist at the angiotensin AT1 receptor.

For research use only. We do not sell to patients.

Angiotensin II (3-8), human TFA Chemical Structure

Angiotensin II (3-8), human TFA Chemical Structure

Size Price Stock Quantity
5 mg USD 90 In-stock
Estimated Time of Arrival: December 31
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
25 mg USD 310 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Angiotensin II (3-8), human TFA:

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Publications Citing Use of MCE Angiotensin II (3-8), human TFA

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Angiotensin II (3-8), human (TFA) is a less effective agonist at the angiotensin AT1 receptor.

IC50 & Target

Angiotensin AT1 receptor[1].

In Vivo

Human Angiotensin II (3-8) causes endothelium-dependent renal cortical vasodilatation, in anaesthetized rats. At doses up to 125 pmol/kg, human Angiotensin II (3-8) is without any cardiovascular effects, but with doses of 1.25 and 12.5 nmol/kg there are dose-dependent increases in mean arterial blood pressure and reductions in renal and mesenteric flows and vascular conductances[1].

Molecular Weight





O=C(O)C(F)(F)F.O=C(N[[email protected]@H](CC1=CC=C(C=C1)O)C(N[[email protected]@H]([[email protected]@H](C)CC)C(N[[email protected]@H](CC2=CNC=N2)C(N3[[email protected]@H](CCC3)C(N[[email protected]@H](CC4=CC=CC=C4)C(O)=O)=O)=O)=O)=O)[[email protected]](C(C)C)N


Room temperature in continental US; may vary elsewhere

Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (56.25 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1249 mL 5.6247 mL 11.2495 mL
5 mM 0.2250 mL 1.1249 mL 2.2499 mL
10 mM 0.1125 mL 0.5625 mL 1.1249 mL
*Please refer to the solubility information to select the appropriate solvent.
Animal Administration

Male Long Evans rats (350-450 g) (n=7) are given increasing bolus doses of AII (1.25, 12.5 and 125 pmol/kg) or human Angiotensin II (3-8) (0.125, 1.25 and 12.5 nmol/kg) in random order, in the morning or afternoon of the same experimental day. Injections are separated by at least 20 min to allow variables to return to baseline[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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